Cardiac resynchronization therapy guided by multimodality cardiac imaging.
Aims Up to 30-45% of implanted patients are non-responders to CRT.We evaluated the role of a 'CRT team' using cardiac magnetic resonance (CMR) and longitudinal myocardial strain to identify the target area defined as the most delayed and viable region for LV pacing. Methods and results A total of 10...
| Publicado en: | European Journal of Heart Failure. Supplements Vol. 18; no. 11; pp. 1375 - 1383 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Nov2016
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122325946&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122325946 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15674215 JE7 jtl: European Journal of Heart Failure. Supplements issn: 15674215 maglogo: N pubinfo: dt: Nov2016 vid: 18 iid: 11 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 122325946 122325946 122325946 10.1002/ejhf.605 122325946 ppf: 1375 ppct: 8 formats: tig: atl: Cardiac resynchronization therapy guided by multimodality cardiac imaging. aug: au: Bertini, Matteo Mele, Donato Malagù, Michele Fiorencis, Andrea Toselli, Tiziano Casadei, Francesca Cannizzaro, Teresa Fragale, Cristina Fucili, Alessandro Campagnolo, Elena Benea, Giorgio Ferrari, Roberto affil: Department of Cardiology, University of Ferrara, S. Anna Hospital, Cona-Ferrara, Italy sug: subj: Cardiac Resynchronization Therapy Heart Failure Magnetic Resonance Spectroscopy Appointments and Schedules Computer Terminals ab: Aims Up to 30-45% of implanted patients are non-responders to CRT.We evaluated the role of a 'CRT team' using cardiac magnetic resonance (CMR) and longitudinal myocardial strain to identify the target area defined as the most delayed and viable region for LV pacing. Methods and results A total of 100 heart failure patients candidates for CRT divided into two groups were enrolled. Group 1 consisted of 50 consecutive patients scheduled for CRT and prospectively included. Group 2 (control) consisted of 50 patients with a CRT device implanted according to standard clinical practice and matched for age, sex, and LVEF with group 1. Patients were evaluated at baseline and at 6-month follow-up. In group 1, patients underwent two-dimensional speckle-tracking assessment of longitudinal myocardial strain and CMR imaging to identify the target area for LV lead pacing. A positive response to CRT was defined as a reduction of ≥15% of the LV end-systolic volume at 6-month follow-up. A total of 39 (78%) patients of group 1 were classified as responders to CRT whilst in group 2, only 28 (56%) were responders (P = 0.019). The 'CRT team' identified as target for LV pacing the lateral area in 30 (60%) patients, and the anterolateral or posterolateral areas in 12 (24%) patients. In 8 (16%) patients, the target was far from the lateral area, in the anterior or posterior areas. The patients with concordant position exhibited the highest positive response (93.1%) to CRT. Conclusions Multimodality cardiac imaging as a guide for CRT implantation is useful to increase response rate. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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