Global Skin Disease Morbidity and Mortality: An Update From the Global Burden of Disease Study 2013.
Importance: Disability secondary to skin conditions is substantial worldwide. The Global Burden of Disease Study 2013 includes estimates of global morbidity and mortality due to skin diseases.Objective: To measure the burden of skin diseases worldwide.Data Sources: For nonfatal estimates, data were...
| Publicado en: | JAMA Dermatology Vol. 153; no. 3 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
American Medical Association
Mar2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122389120&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122389120 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 21686068 FTFQ jtl: JAMA Dermatology issn: 21686068 maglogo: N pubinfo: dt: Mar2017 vid: 153 iid: 3 pid: 30 pub: American Medical Association place: Chicago, Illinois artinfo: ui: 122389120 122389120 NLM28249066 122389120 10.1001/jamadermatol.2016.5538 NLM28249066 122389120 ppct: 1 formats: tig: atl: Global Skin Disease Morbidity and Mortality: An Update From the Global Burden of Disease Study 2013. aug: au: Karimkhani, Chante Dellavalle, Robert P Coffeng, Luc E Flohr, Carsten Hay, Roderick J Langan, Sinéad M Nsoesie, Elaine O Ferrari, Alize J Erskine, Holly E Silverberg, Jonathan I Vos, Theo Naghavi, Mohsen affil: University Hospitals Case Western Medical Center, Cleveland, Ohio2now with Department of Dermatology, University of Colorado, Denver sug: subj: Persons with Disabilities Statistics and Numerical Data World Health Skin Diseases Epidemiology Prevalence Adolescence Aged Aged, 80 and Over Middle Age Skin Diseases Mortality Quality-Adjusted Life Years Skin Diseases Physiopathology Probability Male Female Young Adult Infant, Newborn Child, Preschool Child Infant Adult Scales Adolescent: 13-18 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Infant, Newborn: birth-1 month Child, Preschool: 2-5 years Child: 6-12 years Infant: 1-23 months Adult: 19-44 years Male Female ab: Importance: Disability secondary to skin conditions is substantial worldwide. The Global Burden of Disease Study 2013 includes estimates of global morbidity and mortality due to skin diseases.Objective: To measure the burden of skin diseases worldwide.Data Sources: For nonfatal estimates, data were found by literature search using PubMed and Google Scholar in English and Spanish for years 1980 through 2013 and by accessing administrative data on hospital inpatient and outpatient episodes. Data for fatal estimates were based on vital registration and verbal autopsy data.Study Selection: Skin disease data were extracted from more than 4000 sources including systematic reviews, surveys, population-based disease registries, hospital inpatient data, outpatient data, cohort studies, and autopsy data. Data metrics included incidence, prevalence, remission, duration, severity, deaths, and mortality risk.Data Extraction and Synthesis: Data were extracted by age, time period, case definitions, and other study characteristics. Data points were modeled with Bayesian meta-regression to generate estimates of morbidity and mortality metrics for skin diseases. All estimates were made with 95% uncertainty intervals.Main Outcomes and Measures: Disability-adjusted life years (DALYs), years lived with disability, and years of life lost from 15 skin conditions in 188 countries.Results: Skin conditions contributed 1.79% to the global burden of disease measured in DALYs from 306 diseases and injuries in 2013. Individual skin diseases varied in size from 0.38% of total burden for dermatitis (atopic, contact, and seborrheic dermatitis), 0.29% for acne vulgaris, 0.19% for psoriasis, 0.19% for urticaria, 0.16% for viral skin diseases, 0.15% for fungal skin diseases, 0.07% for scabies, 0.06% for malignant skin melanoma, 0.05% for pyoderma, 0.04% for cellulitis, 0.03% for keratinocyte carcinoma, 0.03% for decubitus ulcer, and 0.01% for alopecia areata. All other skin and subcutaneous diseases composed 0.12% of total DALYs.Conclusions and Relevance: Skin and subcutaneous diseases were the 18th leading cause of global DALYs in Global Burden of Disease 2013. Excluding mortality, skin diseases were the fourth leading cause of disability worldwide. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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