HLA-B57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B57:01-negative subjects.

Background: The presence of the HLA-B*57:01 allele in HIV-infected subjects is associated with a higher risk of abacavir-associated hypersensitivity reaction (ABC HSR). HLA-B*57:01 allele prevalence varies in different populations, but HLA-B*57:01 testing with immunological confirmation has had a ne...

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Detalles Bibliográficos
Publicado en:	BMC Infectious Diseases Vol. 17; pp. 1 - 7
Autores principales:	Small, Catherine Butkus, Margolis, David A., Shaefer, Mark S., Ross, Lisa L.
Formato:	research tables/charts Journal Article
Publicado:	BioMed Central 4/11/2017
Acceso en línea:	Ver este registro en EBSCOhost

HLA-B*57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B*57:01-negative subjects.

HLA-B57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B57:01-negative subjects.