Characterization of benign thyroid nodules with HyperSPACE (Hyper Spectral Analysis for Characterization in Echography) before and after percutaneous laser ablation: a pilot study.

Aims: To evaluate the capability of the HyperSPACE (Hyper SPectral Analysis for Characterization in Echography) method in tissue characterization, in order to provide information for the laser treatment of benign thyroid nodules in respect of conventional B-mode images and elastography.Material and...

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Published in:Medical Ultrasonography Vol. 19; no. 2; pp. 172 - 179
Main Authors: Granchi, Simona, Vannacci, Enrico, Biagi, Elena
Format: research randomized controlled trial Journal Article
Published: Romanian Society of Ultrasonography in Medicine & Biology Jun2017
Online Access:View this record in EBSCOhost
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      dt: Jun2017
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      pub: Romanian Society of Ultrasonography in Medicine & Biology
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        10.11152/mu-1039
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        atl: Characterization of benign thyroid nodules with HyperSPACE (Hyper Spectral Analysis for Characterization in Echography) before and after percutaneous laser ablation: a pilot study.
      aug:
        au:
          Granchi, Simona
          Vannacci, Enrico
          Biagi, Elena
        affil: Department of Information Engineering (DINFO), University of Florence, Florence, Italy
      sug:
        subj:
          Laser Therapy Methods
          Ultrasonography Methods
          Thyroid Nodule Therapy
          Thyroid Nodule
          Imaging, Three-Dimensional Methods
          Image Interpretation, Computer Assisted Methods
          Sensitivity and Specificity
          Reproducibility of Results
          Male
          Thyroid Nodule Pathology
          Middle Age
          Aged, 80 and Over
          Female
          Adult
          Aged
          Human
          Treatment Outcomes
          Validation Studies
          Comparative Studies
          Evaluation Research
          Multicenter Studies
          Randomized Controlled Trials
          Random Assignment
          Middle Aged: 45-64 years
          Aged, 80 & over
          Adult: 19-44 years
          Aged: 65+ years
          Male
          Female
      ab: Aims: To evaluate the capability of the HyperSPACE (Hyper SPectral Analysis for Characterization in Echography) method in tissue characterization, in order to provide information for the laser treatment of benign thyroid nodules in respect of conventional B-mode images and elastography.Material and Methods: The method, based on the spectral analysis of the raw radiofrequency ultrasonic signal, was applied to characterize the nodule before and after laser treatment. Thirty patients (25 females and 5 males, age between 37 and 81 years) with thyroid benign nodule at cytology (Thyr 2) were evaluated by conventional ultrasonography, elastography, and HyperSPACE, before and after laser ablation.Results: The images processed by HyperSPACE exhibit different color distributions that are referred to different tissue features. By calculating the percentages of the color coverages, the analysed nodules were subdivided into 3 groups. Each nodule belonging to the same group experienced, on average, similar necrosis extension. The nodules exhibit different Configurations (colors) distributions that could be indicative of the response of nodular tissue to the laser treatmentConclusions: HyperSPACEcan characterize benign nodules by providing additional information in respect of conventional ultrasound and elastography which is useful for support in the laser treatment of nodules in order to increase the probability of success.
      pubtype: Academic Journal
      doctype:
        research
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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