Tumor-Selective Cytotoxicity of Nitidine Results from Its Rapid Accumulation into Mitochondria.
We identified a nitidine- (NTD-) accumulating organelle and evaluated the net cytotoxicity of accumulated NTD. To evaluate tumor cell selectivity of the drug, we evaluated its selective cytotoxicity against 39 human cancer cell lines (JFCR39 panel), and the profile was compared with those of known a...
| Published in: | BioMed Research International Vol. 2017; pp. 1 - 11 |
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| Main Authors: | , , , , |
| Format: | equations & formulas pictorial research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
4/26/2017
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| Online Access: | View this record in EBSCOhost |