Reduced volume of gray matter in patients with trigeminal neuralgia.
Accumulating evidence from brain structural imaging studies has supported that chronic pain could induce changes in brain gray matter volume. However, few studies have focused on the gray matter alterations of Trigeminal neuralgia (TN). In this study, twenty-eight TN patients (thirteen females; mean...
| Publicado en: | Brain Imaging & Behavior Vol. 11; no. 2; pp. 486 - 493 |
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| Autores principales: | , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122726397&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122726397 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Apr2017 vid: 11 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 122726397 122726397 NLM26899433 122726397 10.1007/s11682-016-9529-2 NLM26899433 122726397 ppf: 486 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Reduced volume of gray matter in patients with trigeminal neuralgia. aug: au: Li, Meng Yan, Jianhao Li, Shumei Wang, Tianyue Zhan, Wenfeng Wen, Hua Ma, Xiaofen Zhang, Yong Tian, Junzhang Jiang, Guihua affil: Department of Medical Imaging , Guangdong No. 2 Provincial People's Hospital , Guangzhou 510317 People's Republic of China sug: subj: Brain Pathology Trigeminal Neuralgia Pathology Gray Matter Pathology Magnetic Resonance Imaging Methods Middle Age Male Female Human Middle Aged: 45-64 years Male Female ab: Accumulating evidence from brain structural imaging studies has supported that chronic pain could induce changes in brain gray matter volume. However, few studies have focused on the gray matter alterations of Trigeminal neuralgia (TN). In this study, twenty-eight TN patients (thirteen females; mean age, 45.86 years ±11.17) and 28 healthy controls (HC; thirteen females; mean age, 44.89 years ±7.67) were included. Using voxel-based morphometry (VBM), we detected abnormalities in gray matter volume in the TN patients. Based on a voxel-wise analysis, the TN group showed significantly decreased gray matter volume in the bilateral superior/middle temporal gyrus (STG/MTG), bilateral parahippocampus, left anterior cingulate cortex (ACC), caudate nucleus, right fusiform gyrus, and right cerebellum compared with the HC. In addition, we found that the gray matter volume in the bilateral STG/MTG was negatively correlated with the duration of TN. These results provide compelling evidence for gray matter abnormalities in TN and suggest that the duration of TN may be a critical factor associated with brain alterations. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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