Diagnostic accuracy of coronary CT angiography using 3rd-generation dual-source CT and automated tube voltage selection: Clinical application in a non-obese and obese patient population.

Purpose: To investigate diagnostic accuracy of 3rd-generation dual-source CT (DSCT) coronary angiography in obese and non-obese patients.Methods: We retrospectively analyzed 76 patients who underwent coronary CT angiography (CCTA) and invasive coronary angiography. Prospectively ECG-triggered acquis...

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Published in:European Radiology Vol. 27; no. 6; pp. 2298 - 2309
Main Authors: Mangold, Stefanie, Wichmann, Julian, Schoepf, U., Caruso, Damiano, Tesche, Christian, Steinberg, Daniel, Varga-Szemes, Akos, Stubenrauch, Andrew, Bayer, Richard, Biancalana, Matthew, Nikolaou, Konstantin, Cecco, Carlo, Wichmann, Julian L, Schoepf, U Joseph, Steinberg, Daniel H, Stubenrauch, Andrew C, Bayer, Richard R 2nd, De Cecco, Carlo N
Format: diagnostic images research tables/charts Journal Article
Published: Springer Nature Jun2017
Online Access:View this record in EBSCOhost
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      dt: Jun2017
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      pub: Springer Nature
      place: New York, New York
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        atl: Diagnostic accuracy of coronary CT angiography using 3rd-generation dual-source CT and automated tube voltage selection: Clinical application in a non-obese and obese patient population.
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        au:
          Mangold, Stefanie
          Wichmann, Julian
          Schoepf, U.
          Caruso, Damiano
          Tesche, Christian
          Steinberg, Daniel
          Varga-Szemes, Akos
          Stubenrauch, Andrew
          Bayer, Richard
          Biancalana, Matthew
          Nikolaou, Konstantin
          Cecco, Carlo
          Wichmann, Julian L
          Schoepf, U Joseph
          Steinberg, Daniel H
          Stubenrauch, Andrew C
          Bayer, Richard R 2nd
          De Cecco, Carlo N
        affil: Division of Cardiology, Department of Medicine , Medical University of South Carolina , Charleston USA
      sug:
        subj:
          Obesity
          Coronary Angiography Standards
          Aged
          Male
          Tomography, X-Ray Computed
          Sensitivity and Specificity
          Radiation Dosage
          Aged, 80 and Over
          Coronary Angiography Methods
          Body Mass Index
          Female
          Adult
          Heart
          Retrospective Design
          Middle Age
          Human
          Aged: 65+ years
          Aged, 80 & over
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: To investigate diagnostic accuracy of 3rd-generation dual-source CT (DSCT) coronary angiography in obese and non-obese patients.Methods: We retrospectively analyzed 76 patients who underwent coronary CT angiography (CCTA) and invasive coronary angiography. Prospectively ECG-triggered acquisition was performed with automated tube voltage selection (ATVS). Patients were dichotomized based on body mass index in groups A (<30 kg/m2, n = 37) and B (≥30 kg/m2, n = 39) and based on tube voltage in groups C (<120 kV, n = 46) and D (120 kV, n = 30). Coronary arteries were assessed for significant stenoses (≥50 % luminal narrowing) and diagnostic accuracy was calculated.Results: Per-patient overall sensitivity, specificity, positive predictive value, negative predictive value (NPV) and accuracy were 96.9 %, 95.5 %, 93.9 %, 97.7 % and 96.1 %, respectively. Sensitivity and NPV were lower in groups B and D compared to groups A and C, but no statistically significant differences were observed (group A vs. B: sensitivity, 100.0 % vs. 93.3 %, p = 0.9493; NPV, 100 % vs. 95.5 %, p = 0.9812; group C vs. D: sensitivity, 100.0 % vs. 92.3 %, p = 0.8462; NPV, 100.0 % vs. 94.1 %, p = 0.8285).Conclusion: CCTA using 3rd-generation DSCT and (ATVS) provides high diagnostic accuracy in both non-obese and obese patients.Key Points: • Coronary CTA provides high diagnostic accuracy in non-obese and obese patients. • Diagnostic accuracy between obese and non-obese patients showed no significant difference. • <120 kV studies were performed in 44 % of obese patients. • Current radiation dose-saving approaches can be applied independent of body habitus.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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