Influences of Duration of Inspiratory Effort, Respiratory Mechanics, and Ventilator Type on Asynchrony With Pressure Support and Proportional Assist Ventilation.

BACKGROUND: Pressure support ventilation (PSV) is often associated with patient-ventilator asynchrony. Proportional assist ventilation (PAV) offers inspiratory assistance proportional to patient effort, minimizing patient-ventilator asynchrony. The objective of this study was to evaluate the influen...

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Publicado en:Respiratory Care Vol. 62; no. 5; pp. 550 - 558
Autores principales: Vasconcelos, Renata S., Sales, Raquel P., de P. Melo, Luíz H., Marinho, Liégina S., Bastos, Vasco P. D., Nogueira, Andréa da N. C., Ferreira, Juliana C., Holanda, Marcelo A.
Formato: research tables/charts Journal Article
Publicado: Mary Ann Liebert, Inc. May2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2017
      vid: 62
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      pub: Mary Ann Liebert, Inc.
      place: New Rochelle, New York
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        122802973
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        10.4187/respcare.05025
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        atl: Influences of Duration of Inspiratory Effort, Respiratory Mechanics, and Ventilator Type on Asynchrony With Pressure Support and Proportional Assist Ventilation.
      aug:
        au:
          Vasconcelos, Renata S.
          Sales, Raquel P.
          de P. Melo, Luíz H.
          Marinho, Liégina S.
          Bastos, Vasco P. D.
          Nogueira, Andréa da N. C.
          Ferreira, Juliana C.
          Holanda, Marcelo A.
        affil: Federal University of Ceará, Fortaleza, Brazil
      sug:
        subj:
          Inspiration, Respiratory
          Respiratory Mechanics
          Pressure Support Ventilation
          Respiration, Artificial Methods
          Lung
          Simulations
          Models, Anatomic
          Tidal Volume
          Time Factors
          Comparative Studies
          Brazil
          Descriptive Statistics
          Waveforms
          Data Analysis Software
          Positive End-Expiratory Pressure
      ab: BACKGROUND: Pressure support ventilation (PSV) is often associated with patient-ventilator asynchrony. Proportional assist ventilation (PAV) offers inspiratory assistance proportional to patient effort, minimizing patient-ventilator asynchrony. The objective of this study was to evaluate the influence of respiratory mechanics and patient effort on patient-ventilator asynchrony during PSV and PAV plus (PAV+). METHODS: We used a mechanical lung simulator and studied 3 respiratory mechanics profiles (normal, obstructive, and restrictive), with variations in the duration of inspiratory effort: 0.5, 1.0, 1.5, and 2.0 s. The Auto-Trak system was studied in ventilators when available. Outcome measures included inspiratory trigger delay, expiratory trigger asynchrony, and tidal volume (VT). RESULTS: Inspiratory trigger delay was greater in the obstructive respiratory mechanics profile and greatest with a effort of 2.0 s (160 ms); cycling asynchrony, particularly delayed cycling, was common in the obstructive profile, whereas the restrictive profile was associated with premature cycling. In comparison with PSV, PAV+ improved patient-ventilator synchrony, with a shorter triggering delay (28 ms vs 116 ms) and no cycling asynchrony in the restrictive profile. VT was lower with PAV+ than with PSV (630 mL vs 837 mL), as it was with the single-limb circuit ventilator (570 mL vs 837 mL). PAV+ mode was associated with longer cycling delays than were the other ventilation modes, especially for the obstructive profile and higher effort values. Auto-Trak eliminated automatic triggering. CONCLUSIONS: Mechanical ventilation asynchrony was influenced by effort, respiratory mechanics, ventilator type, and ventilation mode. In PSV mode, delayed cycling was associated with shorter effort in obstructive respiratory mechanics profiles, whereas premature cycling was more common with longer effort and a restrictive profile. PAV+ prevented premature cycling but not delayed cycling, especially in obstructive respiratory mechanics profiles, and it was associated with a lower VT.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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