Sedentary Behavior Is an Independent Predictor of Mortality in Subjects With COPD.
BACKGROUND: The terms sedentary behavior and physical inactivity have been confusingly mixed. Although the association between physical inactivity and mortality has been shown previously in subjects with COPD, this association had not yet been investigated with regard to sedentarism. The aim of this...
| Publicado en: | Respiratory Care Vol. 62; no. 5; pp. 579 - 588 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
May2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122802977&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122802977 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: May2017 vid: 62 iid: 5 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 122802977 122802977 122802977 10.4187/respcare.05306 122802977 ppf: 579 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Sedentary Behavior Is an Independent Predictor of Mortality in Subjects With COPD. aug: au: Furlanetto, Karina C. Donária, Leila Schneider, Lorena P. Lopes, José R. Ribeiro, Marcos Fernandes, Karen B. P. Hernandes, Nidia A. Pitta, Fabio affil: Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Universidade Estadual de Londrina (UEL), Londrina, Brazil sug: subj: Pulmonary Disease, Chronic Obstructive Mortality Sedentary Behavior Classification Physical Activity Classification Human Reference Values Pulmonary Disease, Chronic Obstructive Prognosis Retrospective Design Wearable Sensors Time Factors Descriptive Statistics Cox Proportional Hazards Model Confidence Intervals P-Value Spirometry Scales Dyspnea ROC Curve Kaplan-Meier Estimator Log-Rank Test Chi Square Test Data Analysis Software Forced Expiratory Volume Male Female Aged Middle Age Mann-Whitney U Test Sensitivity and Specificity Brazil Funding Source Aged: 65+ years Middle Aged: 45-64 years Male Female ab: BACKGROUND: The terms sedentary behavior and physical inactivity have been confusingly mixed. Although the association between physical inactivity and mortality has been shown previously in subjects with COPD, this association had not yet been investigated with regard to sedentarism. The aim of this work was to investigate the impact of sedentary behavior on mortality of subjects with COPD and to propose a cutoff point of sedentarism with prognostic value. METHODS: In this retrospective cohort study, sedentary behavior was assessed with 2 activity monitors (DynaPort and Sensewear armband) in 101 subjects with COPD from 2006 to 2011. Vital status was then ascertained in 2015. The following 6 variables of sedentary behavior were analyzed: average of metabolic equivalent of task (MET)/d (reflecting intensity); time spent/d lying, sitting, and lying + sitting (reflecting duration of sedentary postures); and time spent/d in activities requiring <1.5 MET and <2 MET (reflecting intensity and duration of sedentary time). Cutoff points for sedentarism and their respective prognostic values were investigated for each variable. RESULTS: Forty-one subjects (41%) died over a median (interquartile range) follow-up period of 62 (43-88) months. After adjusting for potential confounders in the Cox regression model, cutoff points from variables that combine duration of sedentary time and intensity <1.5 MET or <2 MET were associated with the increased risk of mortality. The strongest independent cutoff for predicting mortality was ≥8.5 h/d spent in sedentary activities <1.5 MET (area under the curve 0.76; hazard ratio 4.09, 95% CI 1.90-8.78; P < .001). CONCLUSIONS: Sedentary behavior was an independent predictor of mortality in subjects with COPD, even adjusting for moderate-to-vigorous physical activity and a number of other variables. Mortality was higher in subjects with COPD who spend ≥8.5 h/d in activities requiring <1.5 MET. These findings may open room for future studies aiming at decreasing sedentary time as a promising strategy to reduce mortality risk in subjects with COPD. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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