Data extraction and statistical errors: A quantitative critique of Gumley, Braehler, and Macbeth (2014).
Objective While oxytocin has been identified as having therapeutic properties for schizophrenia, the emerging evidence has been mixed which has resulted in meta-analytic reviews. We identified several errors in one such meta-analysis. Here, we highlight these errors, demonstrate the conclusions were...
| Publicado en: | British Journal of Clinical Psychology Vol. 56; no. 2; pp. 208 - 212 |
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| Autores principales: | , |
| Formato: | commentary Journal Article |
| Publicado: |
Wiley-Blackwell
Jun2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=122899120&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 122899120 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01446657 99B jtl: British Journal of Clinical Psychology issn: 01446657 maglogo: Y pubinfo: dt: Jun2017 vid: 56 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 122899120 122899120 122899120 10.1111/bjc.12130 122899120 ppf: 208 ppct: 4 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Data extraction and statistical errors: A quantitative critique of Gumley, Braehler, and Macbeth (2014). aug: au: Williams, Donald R. Bürkner, Paul‐Christian affil: Animal Behavior Graduate Group, University of California, Davis, California, USA sug: subj: Oxytocin Therapeutic Use Schizophrenia Drug Therapy Study Design Data Analysis, Statistical Meta Analysis Oxytocin Administration and Dosage Outcomes (Health Care) Significance Test Administration, Intranasal ab: Objective While oxytocin has been identified as having therapeutic properties for schizophrenia, the emerging evidence has been mixed which has resulted in meta-analytic reviews. We identified several errors in one such meta-analysis. Here, we highlight these errors, demonstrate the conclusions were incorrect, and state the importance of this report. Methods We reproduced the methods of Gumley, Braehler, and Macbeth (), including: outcomes (positive, negative, and total symptoms, as well as general psychopathology) and meta-analytic estimates for fixed and random effect models. Results Whereas Gumley, Braehler, and Macbeth () reported oxytocin had significant effects on three of four outcomes, we show that all effects were non-significant. Conclusions Based on these null results, we hope this report encourages a re-evaluation of intranasal oxytocin as a treatment for schizophrenia. pubtype: Academic Journal doctype: commentary Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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