Language ENvironment Analysis (LENA) in Phelan-McDermid Syndrome: Validity and Suggestions for Use in Minimally Verbal Children with Autism Spectrum Disorder.

Phelan-McDermid syndrome (PMS) is a single-locus cause of developmental delay, autism spectrum disorder, and minimal verbal abilities. There is an urgent need to identify objective outcome measures of expressive language for use in this and other minimally verbal populations. One potential tool is a...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 47; no. 6; pp. 1605 - 1618
Autores principales: Rankine, Jacquelin, Li, Erin, Lurie, Stacey, Rieger, Hillary, Fourie, Emily, Siper, Paige, Wang, A., Buxbaum, Joseph, Kolevzon, Alexander
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jun2017
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Language ENvironment Analysis (LENA) in Phelan-McDermid Syndrome: Validity and Suggestions for Use in Minimally Verbal Children with Autism Spectrum Disorder.
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          Rankine, Jacquelin
          Li, Erin
          Lurie, Stacey
          Rieger, Hillary
          Fourie, Emily
          Siper, Paige
          Wang, A.
          Buxbaum, Joseph
          Kolevzon, Alexander
        affil: Seaver Autism Center for Research and Treatment , Icahn School of Medicine at Mount Sinai , One Gustave L. Levy Place New York 10029 USA
      sug:
        subj:
          Language Disorders Diagnosis
          Autism Spectrum Disorder
          Developmental Disabilities
          Instrument Validation
          Speech and Language Assessment
          Human
          Syndrome
          Clinical Assessment Tools
          Reliability and Validity
      ab: Phelan-McDermid syndrome (PMS) is a single-locus cause of developmental delay, autism spectrum disorder, and minimal verbal abilities. There is an urgent need to identify objective outcome measures of expressive language for use in this and other minimally verbal populations. One potential tool is an automated language processor called Language ENvironment Analysis (LENA). LENA was used to obtain over 542 h of audio in 18 children with PMS. LENA performance was adequate in a subset of children with PMS, specifically younger children and those with fewer stereotypic vocalizations. One LENA-derived language measure, Vocalization Ratio, had improved accuracy in this sample and may represent a novel expressive language measure for use in severely affected populations.
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    language: English
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