A case-based reasoning system based on weighted heterogeneous value distance metric for breast cancer diagnosis.

Objective: We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential...

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Publicado en:Artificial Intelligence in Medicine Vol. 77; pp. 31 - 48
Autores principales: Gu, Dongxiao, Liang, Changyong, Zhao, Huimin
Formato: research Journal Article
Publicado: Elsevier B.V. Mar2017
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Artificial Intelligence in Medicine
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      dt: Mar2017
      vid: 77
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      pub: Elsevier B.V.
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        10.1016/j.artmed.2017.02.003
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        atl: A case-based reasoning system based on weighted heterogeneous value distance metric for breast cancer diagnosis.
      aug:
        au:
          Gu, Dongxiao
          Liang, Changyong
          Zhao, Huimin
        affil: School of Management, Hefei University of Technology, 193 Tunxi Road, Hefei, Anhui, 230009, China
      sug:
        subj:
          Decision Support Techniques
          Breast Neoplasms
          Expert Systems
          Female
          ROC Curve
          Algorithms
          Software
          Human
          Female
      ab: Objective: We present the implementation and application of a case-based reasoning (CBR) system for breast cancer related diagnoses. By retrieving similar cases in a breast cancer decision support system, oncologists can obtain powerful information or knowledge, complementing their own experiential knowledge, in their medical decision making.Methods: We observed two problems in applying standard CBR to this context: the abundance of different types of attributes and the difficulty in eliciting appropriate attribute weights from human experts. We therefore used a distance measure named weighted heterogeneous value distance metric, which can better deal with both continuous and discrete attributes simultaneously than the standard Euclidean distance, and a genetic algorithm for learning the attribute weights involved in this distance measure automatically. We evaluated our CBR system in two case studies, related to benign/malignant tumor prediction and secondary cancer prediction, respectively.Result: Weighted heterogeneous value distance metric with genetic algorithm for weight learning outperformed several alternative attribute matching methods and several classification methods by at least 3.4%, reaching 0.938, 0.883, 0.933, and 0.984 in the first case study, and 0.927, 0.842, 0.939, and 0.989 in the second case study, in terms of accuracy, sensitivity×specificity, F measure, and area under the receiver operating characteristic curve, respectively.Conclusion: The evaluation result indicates the potential of CBR in the breast cancer diagnosis domain.
      pubtype: Academic Journal
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        Journal Article
      ougenre: Article
    language: English
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