An enhanced random walk algorithm for delineation of head and neck cancers in PET studies.

An algorithm for delineating complex head and neck cancers in positron emission tomography (PET) images is presented in this article. An enhanced random walk (RW) algorithm with automatic seed detection is proposed and used to make the segmentation process feasible in the event of inhomogeneous lesi...

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Publicado en:Medical & Biological Engineering & Computing Vol. 55; no. 6; pp. 897 - 909
Autores principales: Stefano, Alessandro, Vitabile, Salvatore, Russo, Giorgio, Ippolito, Massimo, Sabini, Maria, Sardina, Daniele, Gambino, Orazio, Pirrone, Roberto, Ardizzone, Edoardo, Gilardi, Maria, Sabini, Maria Gabriella, Gilardi, Maria Carla
Formato: diagnostic images equations & formulas pictorial research Journal Article
Publicado: Springer Nature Jun2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2017
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11517-016-1571-0
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        atl: An enhanced random walk algorithm for delineation of head and neck cancers in PET studies.
      aug:
        au:
          Stefano, Alessandro
          Vitabile, Salvatore
          Russo, Giorgio
          Ippolito, Massimo
          Sabini, Maria
          Sardina, Daniele
          Gambino, Orazio
          Pirrone, Roberto
          Ardizzone, Edoardo
          Gilardi, Maria
          Sabini, Maria Gabriella
          Gilardi, Maria Carla
        affil: Department of Biopathology and Medical Biotechnologies (DIBiMED) , University of Palermo , Palermo Italy
      sug:
        subj:
          Tomography, Emission-Computed Methods
          Head and Neck Neoplasms Diagnosis
          Image Processing, Computer Assisted Methods
          Phantoms, Imaging
          Algorithms
          Human
      ab: An algorithm for delineating complex head and neck cancers in positron emission tomography (PET) images is presented in this article. An enhanced random walk (RW) algorithm with automatic seed detection is proposed and used to make the segmentation process feasible in the event of inhomogeneous lesions with bifurcations. In addition, an adaptive probability threshold and a k-means based clustering technique have been integrated in the proposed enhanced RW algorithm. The new threshold is capable of following the intensity changes between adjacent slices along the whole cancer volume, leading to an operator-independent algorithm. Validation experiments were first conducted on phantom studies: High Dice similarity coefficients, high true positive volume fractions, and low Hausdorff distance confirm the accuracy of the proposed method. Subsequently, forty head and neck lesions were segmented in order to evaluate the clinical feasibility of the proposed approach against the most common segmentation algorithms. Experimental results show that the proposed algorithm is more accurate and robust than the most common algorithms in the literature. Finally, the proposed method also shows real-time performance, addressing the physician's requirements in a radiotherapy environment.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        Journal Article
      ougenre: Article
    language: English
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