The effects of alcoholism and smoking on advanced cancer patients admitted to an acute supportive/palliative care unit.

Aim: The aim of this prospective study was to determine the characteristics and symptom burden of advanced cancer patients with alcoholism problems and smoking, who were referred to an acute palliative/supportive care unit (ASPCU) of a comprehensive cancer center.Methods: Patients' characteristics,...

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Publicado en:Supportive Care in Cancer Vol. 25; no. 7; pp. 2147 - 2154
Autores principales: Mercadante, Sebastiano, Adile, Claudio, Ferrera, Patrizia, Casuccio, Alessandra
Formato: research tables/charts Journal Article
Publicado: Springer Nature Jul2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2017
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      pub: Springer Nature
      place: New York, New York
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        atl: The effects of alcoholism and smoking on advanced cancer patients admitted to an acute supportive/palliative care unit.
      aug:
        au:
          Mercadante, Sebastiano
          Adile, Claudio
          Ferrera, Patrizia
          Casuccio, Alessandra
      sug:
        subj:
          Palliative Care Methods
          Neoplasms Complications
          Alcoholism Complications
          Smoking
          Neoplasms Pathology
          Female
          Neoplasms Therapy
          Aged
          Male
          Middle Age
          Prospective Studies
          Questionnaires
          Scales
          Human
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Aim: The aim of this prospective study was to determine the characteristics and symptom burden of advanced cancer patients with alcoholism problems and smoking, who were referred to an acute palliative/supportive care unit (ASPCU) of a comprehensive cancer center.Methods: Patients' characteristics, indications for admission, kind of admission, awareness of prognosis, and anticancer treatments were recorded. The Edmonton Symptom Assessment Scale (ESAS) was used to assess physical and psychological symptoms, and the CAGE questionnaire for the diagnosis of alcoholism. Patients were also divided in three groups: persistent smokers (PS), former smokers (FS), and non-smokers (NS). The Memorial Delirium Assessment Scale (MDAS) was used to assess the cognitive status of patients. Analgesic drugs and their doses at admission and discharge were recorded, as well opioid escalation index during hospital stay.Results: Three hundred fourteen consecutive cancer patients were surveyed. Forty-seven (14.9%), 143 (45.5%), and 124 (39.5%) subjects were PS-patients, FS-patients, and NS-patients, respectively. Sixteen patients were CAGE-positive. Females were more frequently NS, while males were more frequently FS (p = 0.0005). Statistical differences were also observed in disease awareness among the categories of smoking (p = 0.048). No statistical differences were found in ESAS items, except for drowsiness at T0 in NS-patients. Differences were found in OME and OEI, although the large variability of data did not determined a statistical difference. Higher values of nausea (at T0, p = 0.0005), dyspnea (at T0 and TX, p = 0.08 and 0.023, respectively), and well-being (at TX p = 0.003) were reported in CAGE-positive patients. No correlation was found between CAGE-positive patients and smokers.Conclusion: Although smoking and alcoholism have obvious implications in advanced cancer patients, data remain controversial, as present data did provide limited data to confirm risk factors for advanced cancer patients. Clinical response was not strongly influenced by these risk factors.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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