Language Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy.

Purpose: The purpose of this study was to investigate characteristics of language development in relation to brain magnetic resonance imaging (MRI) characteristics and the other contributing factors to language development in children with cerebral palsy (CP). Method: The study included 172 children...

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Publicado en:Journal of Speech, Language & Hearing Research Vol. 60; no. 5; pp. 1330 - 1339
Autores principales: Ja Young Choi, Yoon Seong Choi, Eun Sook Park
Formato: Artículo
Publicado: American Speech-Language-Hearing Association May2017
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2017
      vid: 60
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      pub: American Speech-Language-Hearing Association
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        10.1044/2016_JSLHR-L-16-0281
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        atl: Language Development and Brain Magnetic Resonance Imaging Characteristics in Preschool Children With Cerebral Palsy.
      aug:
        au:
          Ja Young Choi
          Yoon Seong Choi
          Eun Sook Park
        affil:
          Department of Rehabilitation Medicine, Severance Hospital, Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
          Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
      su:
        Preschool children
        Cognition
        Language acquisition
        Retrospective studies
        Language awareness in children
        Magnetic resonance imaging of the brain
        Children with cerebral palsy
        White matter (Nerve tissue)
        Language ability testing
        Expressive language disorder
        Gray matter (Nerve tissue)
        Wounds & injuries
        Brain
        Radiography
        Cerebral palsy
        Statistical correlation
        Magnetic resonance imaging
        Nonparametric statistics
        Statistics
        T-test (Statistics)
        Data analysis
        Multiple regression analysis
        Data analysis software
        Tertiary care
        Mann Whitney U Test
        Kruskal-Wallis Test
        Diagnosis
      sug:
        subj:
          Preschool children
          Cognition
          Language acquisition
          Retrospective studies
          Diagnostic Imaging Centers
          Specialty (except Psychiatric and Substance Abuse) Hospitals
          Language awareness in children
          Magnetic resonance imaging of the brain
          Children with cerebral palsy
          White matter (Nerve tissue)
          Language ability testing
          Expressive language disorder
          Gray matter (Nerve tissue)
          Wounds & injuries
          Brain
          Radiography
          Cerebral palsy
          Statistical correlation
          Magnetic resonance imaging
          Nonparametric statistics
          Statistics
          T-test (Statistics)
          Data analysis
          Multiple regression analysis
          Data analysis software
          Tertiary care
          Mann Whitney U Test
          Kruskal-Wallis Test
          Diagnosis
      ab: Purpose: The purpose of this study was to investigate characteristics of language development in relation to brain magnetic resonance imaging (MRI) characteristics and the other contributing factors to language development in children with cerebral palsy (CP). Method: The study included 172 children with CP who underwent brain MRI and language assessments between 3 and 7 years of age. The MRI characteristics were categorized as normal, malformation, periventricular white matter lesion (PVWL), deep gray matter lesion, focal infarct, cortical/subcortical lesion, and others. Neurodevelopmental outcomes such as ambulatory status, manual ability, cognitive function, and accompanying impairments were assessed. Results: Both receptive and expressive language development quotients (DQs) were significantly related to PVWL or deep gray matter lesion severity. In multivariable analysis, only cognitive function was significantly related to receptive language development, whereas ambulatory status and cognitive function were significantly associated with expressive language development. More than one third of the children had a language developmental discrepancy between receptive and expressive DQs. Children with cortical/subcortical lesions were at high risk for this discrepancy. Conclusions: Cognitive function is a key factor for both receptive and expressive language development. In children with PVWL or deep gray matter lesion, lesion severity seems to be useful to predict language development.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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