Magnetic resonance elastography in the assessment of hepatic fibrosis: a study comparing transient elastography and histological data in the same patients.
Purpose: To evaluate the quantitative measurement of liver stiffness (LS), compare the diagnostic performance of magnetic resonance elastography (MRE) and ultrasound-based transient elastography (TE), and evaluate two different MRE-based LS measurement methods. Methods: Between October 2013 and Janu...
| Publicado en: | Abdominal Radiology Vol. 42; no. 6; pp. 1659 - 1667 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Jun2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123347921&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 123347921 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Jun2017 vid: 42 iid: 6 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 123347921 144066970 10.1007/s00261-017-1045-3 123347921 ppf: 1659 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Magnetic resonance elastography in the assessment of hepatic fibrosis: a study comparing transient elastography and histological data in the same patients. aug: au: Toguchi, Masafumi Tsurusaki, Masakatsu Yada, Norihisa Sofue, Keitaro Hyodo, Tomoko Onoda, Minori Numoto, Isao Matsuki, Mitsuru Imaoka, Izumi Kudo, Masatoshi Murakami, Takamichi affil: Department of Radiology, Faculty of Medicine , Kindai University , 377-2 Ohno-Higashi Osaka-Sayama 589-8511 Japan sug: ab: Purpose: To evaluate the quantitative measurement of liver stiffness (LS), compare the diagnostic performance of magnetic resonance elastography (MRE) and ultrasound-based transient elastography (TE), and evaluate two different MRE-based LS measurement methods. Methods: Between October 2013 and January 2015, 116 consecutive patients with chronic liver disease underwent MRE to measure LS (kilopascals; kPa). Of the 116 patients, 51 patients underwent both TE and liver biopsy, and the interval between the liver biopsy and both the MRE and TE was less than 90 days. MRE-derived LS values were measured on the anterior segment of the right lobe (single small round regions of interest per slice; srROIs) and whole right lobe of the liver (free hand region of interest; fhROI), and these values were correlated with pathological fibrosis grades and diagnostic performance. Results: Pathological fibrosis stage was significantly correlated with srROIs ( r = 0.87, p < 0.001), fhROI ( r = 0.80, p < 0.001), and TE ( r = 0.73, p < 0.001). For detection of significant fibrosis (≥F2), advanced fibrosis (≥F3), and cirrhosis, the area under the curve (AUC) associated with the srROIs was largest, and there was a significant difference between srROIs and TE (0.93 vs. 0.82, p = 0.006), srROIs and fhROI (0.93 vs. 0.89, p = 0.04) for detection of ≥F2. For advanced fibrosis and cirrhosis detection, AUCs were not significant (0.92-0.96). Conclusions: MRE and TE detected liver fibrosis with comparable accuracy. In particular, the srROIs method was effective for detecting of significant fibrosis. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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