Diagnostic performance of calcification-suppressed coronary CT angiography using rapid kilovolt-switching dual-energy CT.
Objectives: Multi-detector-row computed tomography angiography (MDCTA) plays an important role in the assessment of patients with suspected coronary artery disease. However, MDCTA tends to overestimate stenosis in calcified coronary artery lesions. The aim of our study was to evaluate the diagnostic...
| Publicado en: | European Radiology Vol. 27; no. 7; pp. 2794 - 2802 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Jul2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123476729&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 123476729 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Jul2017 vid: 27 iid: 7 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 123476729 123476729 144101460 NLM27966040 123476729 10.1007/s00330-016-4675-x NLM27966040 123476729 ppf: 2794 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Diagnostic performance of calcification-suppressed coronary CT angiography using rapid kilovolt-switching dual-energy CT. aug: au: Yunaga, Hiroto Ohta, Yasutoshi Kaetsu, Yasuhiro Kitao, Shinichiro Watanabe, Tomomi Furuse, Yoshiyuki Yamamoto, Kazuhiro Ogawa, Toshihide affil: Division of Radiology, Department of Pathophysiological Therapeutic Science, Faculty of Medicine , Tottori University , 36-1, Nishi-cho Yonago City 683-8504 Japan sug: subj: Coronary Stenosis Diagnosis Calcinosis Diagnosis Radiographic Image Enhancement Standards Coronary Vessels Coronary Angiography Standards Multidetector Computed Tomography Standards Human Middle Age Aged Reproducibility of Results Male Weights and Measures Female Validation Studies Comparative Studies Evaluation Research Multicenter Studies Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Objectives: Multi-detector-row computed tomography angiography (MDCTA) plays an important role in the assessment of patients with suspected coronary artery disease. However, MDCTA tends to overestimate stenosis in calcified coronary artery lesions. The aim of our study was to evaluate the diagnostic performance of calcification-suppressed material density (MD) images produced by using a single-detector single-source dual-energy computed tomography (ssDECT).Methods: We enrolled 67 patients with suspected or known coronary artery disease who underwent ssDECT with rapid kilovolt-switching (80 and 140 kVp). Coronary artery stenosis was evaluated on the basis of MD images and virtual monochromatic (VM) images. The diagnostic performance of the two methods for detecting coronary artery disease was compared with that of invasive coronary angiography as a reference standard.Results: We evaluated 239 calcified segments. In all the segments, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy for detecting significant stenosis were respectively 88%, 88%, 75%, 95% and 88% for the MD images, 91%, 71%, 56%, 95% and 77% for the VM images. PPV was significantly higher on the MD images than on the VM images (P < 0.0001).Conclusions: Calcification-suppressed MD images improved PPV and diagnostic performance for calcified coronary artery lesions.Key Points: • Computed tomography angiography tends to overestimate stenosis in calcified coronary artery. • Dual-energy CT enables us to suppress calcification of coronary artery lesions. • Calcification-suppressed material density imaging reduces false-positive diagnosis of calcified lesion. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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