New Mydriasis-Free Electroretinogram Recorded with Skin Electrodes in Healthy Subjects.

Purpose. To evaluate the reproducibility and consistency of the new mydriasis-free electroretinogram (ERG) with a skin electrode (RETeval) device, to determine the normative values of parameters, and to clarify the usefulness of pupil records to colored-light stimulus. Methods. A total of 100 eyes o...

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Publicado en:BioMed Research International Vol. 2017; pp. 1 - 8
Autores principales: Asakawa, Ken, Amino, Kana, Iwase, Machiho, Kusayanagi, Yuki, Nakamura, Akiho, Suzuki, Rio, Yuuki, Takashi, Ishikawa, Hitoshi
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell 6/20/2017
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
      issn: 23146133
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      dt: 6/20/2017
      vid: 2017
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2017/8539747
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        atl: New Mydriasis-Free Electroretinogram Recorded with Skin Electrodes in Healthy Subjects.
      aug:
        au:
          Asakawa, Ken
          Amino, Kana
          Iwase, Machiho
          Kusayanagi, Yuki
          Nakamura, Akiho
          Suzuki, Rio
          Yuuki, Takashi
          Ishikawa, Hitoshi
        affil: Department of Orthoptics and Visual Science, School of Allied Health Sciences, Kitasato University, Kanagawa, Japan
      sug:
        subj:
          Mydriatics
          Electroretinography Methods
          Electrodes
          Skin Anatomy and Histology
          Human
          Ophthalmology
          Reproducibility of Results
          Technology, Medical
          Retina Anatomy and Histology
          Pupil Anatomy and Histology
          Correlation Coefficient
          Data Analysis Software
          Descriptive Statistics
          Confidence Intervals
          Miosis Diagnosis
          Retinal Diseases Diagnosis
          Eye Anatomy and Histology
          Funding Source
      ab: Purpose. To evaluate the reproducibility and consistency of the new mydriasis-free electroretinogram (ERG) with a skin electrode (RETeval) device, to determine the normative values of parameters, and to clarify the usefulness of pupil records to colored-light stimulus. Methods. A total of 100 eyes of 50 healthy subjects (mean age, 21.4 years) were enrolled. The diagnostic parameters obtained by the RETeval device were examined under the following conditions. The reproducibility was determined with the coefficient of variation (CV). The consistency was examined by intraclass correlation coefficients (ICCs). The mean value and the normal range were analyzed with a 95% confidence interval as the normative values of parameters. The correlation of parameters to pupil records (area ratio, constriction ratio) and flicker ERG was also examined in the diabetic retinopathy assessment protocol. Results. From the CV for each of the two measurements, the amplitude has a low reproducibility compared with the implicit time. Generally good consistency was obtained with both ERG parameters (ICCs = 0.48–0.92). Moderate correlations were found for the white-, red-, and blue-light stimulus in the area ratio and the constriction ratio, respectively (r = 0.44–0.62; P = 0.010–<0.0001). No correlation was observed between pupil and flicker parameters (r = 0.06–0.34; P = 0.646–0.051). Conclusions. The RETeval device was suggested as a possible screening device to detect the visual afferent diseases by evaluating in combination with the ERG recording and the colored-light pupil response.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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