An Unusual Association of Pyoderma Gangrenosum with Henoch-Schonlein Purpura in a Child.
Henoch-Schonlein purpura (HSP) is a systemic vasculitis affecting small vessels. Pyoderma gangrenosum (PG) is an uncommon, non-infectious, neutrophilic dermatosis. A sixteen-year-old boy was admitted to our clinic with arthralgia, palpable purpuric rush and a wound on the left lower extremity. Derma...
| Publicado en: | Medical Bulletin of Haseki / Haseki Tip Bulteni Vol. 55; no. 2; pp. 157 - 161 |
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| Autores principales: | , , , , |
| Formato: | case study pictorial Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Jun2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123724660&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 123724660 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13020072 B6K1 jtl: Medical Bulletin of Haseki / Haseki Tip Bulteni issn: 13020072 maglogo: N pubinfo: dt: Jun2017 vid: 55 iid: 2 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 123724660 123724660 123724660 10.4274/haseki.3369 123724660 ppf: 157 ppct: 4 formats: tig: atl: An Unusual Association of Pyoderma Gangrenosum with Henoch-Schonlein Purpura in a Child. aug: au: Duru, Nilgün Selçuk Petan, Melike İrem Suiçmez, Hale Sandıkçı Elevli, Murat Kasapçopur, Özgür affil: University of Health Sciences Haseki Training and Research Hospital, Clinic of Pediatrics, İstanbul, Turkey sug: subj: Pyoderma Gangrenosum Purpura, Schoenlein-Henoch Consent (Research) Lower Extremity Immunoglobulins Vasculitis Child Adult Child: 6-12 years Adult: 19-44 years ab: Henoch-Schonlein purpura (HSP) is a systemic vasculitis affecting small vessels. Pyoderma gangrenosum (PG) is an uncommon, non-infectious, neutrophilic dermatosis. A sixteen-year-old boy was admitted to our clinic with arthralgia, palpable purpuric rush and a wound on the left lower extremity. Dermatological examination revealed an ulcer 3x3 cm in diameter covered with necrotic material and surrounded by a bluish ring. The lesion was found to be clinically compatible with pyoderma gangrenosum. Histological examination of the biopsy material taken from the purpuric rush was compatible with leukocytoclastic vasculitis. Direct immunofluorescence showed IgA class antibody and C3 deposition within the dermal capillaries. These findings were suggestive of HSP. We report a case of HSP with PG like ulcer. To the best of our knowledge, only one adult case of HSP with PG has been reported so far. Henoch-Schönlein purpurası (HSP) küçük damarları etkileyen bir sistemik vaskülitdir. Piyoderma gangrenozum (PG) ise nadir rastlanan, enfeksiyöz olmayan bir nötrofilik dermatozdur. On altı yaşındaki erkek hasta kliniğimize artralji, palpabl purpura ve sol alt ekstremite üzerinde bir yara ile başvurdu. Dermatolojik muayenesinde tabanı nekrotik materyal ile kaplı, mavimsi bir halka ile çevrili 3x3 cm çapında bir ülser gözlendi. Lezyon klinik olarak PG ile uyumlu bulundu. Purpurik döküntüden alınan biyopsi materyalinin histolojik incelemesi lökoklastik vaskülit ile uyumluydu. Direkt immünofluoresans dermal kapillerler içinde IgA sınıfı antikorlar ve C3 depolanmaları gösterdi. Bulgular HSP tanısı ile uyumluydu. Bilgilerimize göre şimdiye kadar PG ile birlikte HSP olgusu yalnız bir erişkin hastada sunulmuştur. pubtype: Academic Journal doctype: case study pictorial Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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