Abuse-related effects of subtype-selective GABA receptor positive allosteric modulators in an assay of intracranial self-stimulation in rats.

Rationale: GABA positive allosteric modulators (GABA PAMs), such as diazepam and zolpidem, are used clinically for anxiety and insomnia, but abuse liability is a concern. Novel GABA PAMS may have lower abuse liability while retaining clinical utility. Objective: The present study compared abuse-rela...

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Publicado en:Psychopharmacology Vol. 234; no. 14; pp. 2091 - 2102
Autores principales: Schwienteck, Kathryn, Li, Guanguan, Poe, Michael, Cook, James, Banks, Matthew, Stevens Negus, S.
Formato: Journal Article
Publicado: Springer Nature Jul2017
Acceso en línea:Ver este registro en EBSCOhost