Post-mortem whole-body magnetic resonance imaging of human fetuses: a comparison of 3-T vs. 1.5-T MR imaging with classical autopsy.
Objective: To prospectively compare diagnostic accuracy of fetal post-mortem whole-body MRI at 3-T vs. 1.5-T.Methods: Between 2012 and 2015, post-mortem MRI at 1.5-T and 3-T was performed in fetuses after miscarriage/stillbirth or termination. Clinical MRI diagnoses were assessed using a confidence...
| Publicado en: | European Radiology Vol. 27; no. 8; pp. 3542 - 3554 |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123837840&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 123837840 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09387994 NPH jtl: European Radiology issn: 09387994 maglogo: N pubinfo: dt: Aug2017 vid: 27 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 123837840 123837840 144082553 NLM28116518 123837840 10.1007/s00330-016-4725-4 NLM28116518 123837840 ppf: 3542 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Post-mortem whole-body magnetic resonance imaging of human fetuses: a comparison of 3-T vs. 1.5-T MR imaging with classical autopsy. aug: au: Kang, Xin Cannie, Mieke Arthurs, Owen Segers, Valerie Fourneau, Catherine Bevilacqua, Elisa Cos Sanchez, Teresa Sebire, Neil Jani, Jacques Cannie, Mieke M Arthurs, Owen J Sebire, Neil J Jani, Jacques C affil: Department of Obstetrics and Gynecology, Fetal Medicine Unit , University Hospital Brugmann, Université Libre de Bruxelles , Place A. Van Gehuchten 4 1020 Brussels Belgium sug: subj: Perinatal Death Abortion, Spontaneous Fetal Diseases Diagnostic Errors Human Brain Brain Pathology Gestational Age Thorax Fetus Pathology Autopsy Methods Myocardium Pathology Abortion, Induced Diagnostic Imaging Methods Heart Prospective Studies Thorax Pathology Magnetic Resonance Imaging Methods Female Fetal Diseases Pathology Pregnancy Abortion, Spontaneous Pathology Validation Studies Comparative Studies Evaluation Research Multicenter Studies Funding Source Fetus Fetus, conception to birth Female ab: Objective: To prospectively compare diagnostic accuracy of fetal post-mortem whole-body MRI at 3-T vs. 1.5-T.Methods: Between 2012 and 2015, post-mortem MRI at 1.5-T and 3-T was performed in fetuses after miscarriage/stillbirth or termination. Clinical MRI diagnoses were assessed using a confidence diagnostic score and compared with classical autopsy to derive a diagnostic error score. The relation of diagnostic error for each organ group with gestational age was calculated and 1.5-T with 3-T was compared with accuracy analysis.Results: 135 fetuses at 12-41 weeks underwent post-mortem MRI (followed by conventional autopsy in 92 fetuses). For all organ groups except the brain, and for both modalities, the diagnostic error decreased with gestation (P < 0.0001). 3-T MRI diagnostic error was significantly lower than that of 1.5-T for all anatomic structures and organ groups, except the orbits and brain. This difference was maintained for fetuses <20 weeks gestation. Moreover, 3-T was associated with fewer non-diagnostic scans and greater concordance with classical autopsy than 1.5-T MRI, especially for the thorax, heart and abdomen in fetuses <20 weeks.Conclusion: Post-mortem fetal 3-T MRI improves confidence scores and overall accuracy compared with 1.5-T, mainly for the thorax, heart and abdomen of fetuses <20 weeks of gestation.Key Points: • In PM-MRI, diagnostic error using 3-T is lower than that with 1.5-T. • In PM-MRI, diagnostic scan rate is higher using 3-T than 1.5-T. • In PM-MRI, concordance with classical autopsy increases with 3-T. • PM-MRI using 3-T is particularly interesting for thoracic and abdominal organs. • PM-MRI using 3-T is particularly interesting for fetuses < 20 weeks' gestation. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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