Endogenous endophthalmitis caused by Var. Gattii mimicking choroidal tumor: From positron-emission tomography/computed tomography to histopathology.

A 60-year-old immunocompetent female with pneumonia history about 10 years ago suffered from blurred vision overall survival for 3 weeks. Common cold with headache and unintentional body weight loss was also noted recently. Choroidal detachment simulating choroidal tumor was observed in the temporal...

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Publicado en:Indian Journal of Ophthalmology Vol. 65; no. 6; pp. 526 - 529
Autores principales: Lin, Chun-Ju, Chen, Wen-Lu, Lin, Jane-Ming, Tien, Peng-Tai, Tsai, Yi-Yu
Formato: case study Journal Article
Publicado: Wolters Kluwer India Pvt Ltd Jun2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun2017
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      pub: Wolters Kluwer India Pvt Ltd
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        atl: Endogenous endophthalmitis caused by Var. Gattii mimicking choroidal tumor: From positron-emission tomography/computed tomography to histopathology.
      aug:
        au:
          Lin, Chun-Ju
          Chen, Wen-Lu
          Lin, Jane-Ming
          Tien, Peng-Tai
          Tsai, Yi-Yu
        affil: School of Medicine, College of Medicine, China Medical University; Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan, ROC
      sug:
        subj:
          Biopsy Methods
          Cryptococcus
          Cryptococcosis Diagnosis
          Eye Infections, Fungal Diagnosis
          Endophthalmitis Diagnosis
          Uveal Neoplasms Diagnosis
          Middle Age
          Eye Infections, Fungal Microbiology
          Cryptococcosis Microbiology
          Diagnosis, Differential
          Vitreous Body Microbiology
          Endophthalmitis Microbiology
          Female
          Middle Aged: 45-64 years
          Female
      ab: A 60-year-old immunocompetent female with pneumonia history about 10 years ago suffered from blurred vision overall survival for 3 weeks. Common cold with headache and unintentional body weight loss was also noted recently. Choroidal detachment simulating choroidal tumor was observed in the temporal quadrant. The 18F-fluoro-2-deoxyglucose (FDG) positron-emission tomography/computed tomography (CT) scan showed focal, mild to moderate FDG uptake in the left lateral orbit, and an enhanced lesion was seen on the recent CT scan. The suspicious choroidal tumor became larger in a week. Phacoemulsification, vitrectomy, and retinal biopsies were performed. Histochemical study of the retinal specimens established the diagnosis of endogenous cryptococcal endophthalmitis. Vitreous culture yielded Cryptococcus neoformans var. gattii. Systemic and topical voriconazole eliminated the infection. In the literature, endogenous endophthalmitis caused by C. neoformans var. gattii has not been reported in detail. The key to successful management lies in early diagnosis. If clinical improvement could not be achieved after conventional management and imaging studies have failed to yield a definite diagnosis, retinal biopsy can be considered.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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