Nickel Sequestration by the Host-Defense Protein Human Calprotectin.

The human innate immune protein calprotectin (CP, S100A8/S100A9 oligomer, calgranulin A/calgranulin B oligomer, MRP-8/MRP-14 oligomer) chelates a number of first-row transition metals, including Mn(II), Fe(II), and Zn(II), and can withhold these essential nutrients from microbes. Here we elucidate t...

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Publicado en:	Journal of the American Chemical Society Vol. 139; no. 26; pp. 8828 - 8837
Autores principales:	Nakashige, Toshiki G., Zygiel, Emily M., Drennan, Catherine L., Nolan, Elizabeth M.
Formato:	Artículo
Publicado:	American Chemical Society 7/5/2017
Materias:	Sequestration (Chemistry) Lectins Coordinate covalent bond Chelation Staphylococcus aureus Enzyme inhibitors Urease
Acceso en línea:	Ver este registro en EBSCOhost