The effects of pharmacist interventions on adult outpatients with cancer: A systematic review.
What is known and objectives Most antineoplastic drugs are highly toxic and have low therapeutic indexes, which can result in drug-related problems. In this context, pharmacist interventions may play an important role in the success of the treatment. The objective of this study was to examine the ef...
| Publicado en: | Journal of Clinical Pharmacy & Therapeutics Vol. 42; no. 4; pp. 414 - 426 |
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| Autores principales: | , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=123996345&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 123996345 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 02694727 EV4 jtl: Journal of Clinical Pharmacy & Therapeutics issn: 02694727 maglogo: Y pubinfo: dt: Aug2017 vid: 42 iid: 4 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 123996345 123996345 123996345 10.1111/jcpt.12562 123996345 ppf: 414 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: The effects of pharmacist interventions on adult outpatients with cancer: A systematic review. aug: au: Colombo, L. R. P. Aguiar, P. M. Lima, T. M. Storpirtis, S. affil: Department of Pharmacy, University of São Paulo, São Paulo Brazil sug: subj: Antineoplastic Agents Administration and Dosage Neoplasms Drug Therapy Pharmacists Professional Role Treatment Outcomes Human Systematic Review PubMed Outpatients Cancer Patients Patient Satisfaction Nausea and Vomiting Prevention and Control Medication Compliance Oncologic Care Middle Age Middle Aged: 45-64 years ab: What is known and objectives Most antineoplastic drugs are highly toxic and have low therapeutic indexes, which can result in drug-related problems. In this context, pharmacist interventions may play an important role in the success of the treatment. The objective of this study was to examine the effects of pharmacist interventions on adult outpatients with cancer using antineoplastic drugs. Methods A literature search was performed using PubMed, ISI Web of Science and LILACS databases from January 1990 to April 2016, using MeSH terms or text words related to pharmacist interventions, cancer and outpatient care. Studies published in English, Portuguese or Spanish on the effects of pharmacist interventions in outcome measures in adult outpatients with cancer were included. Two independent authors performed study selection and data extraction with a consensus process. The articles were analysed according to previously established criteria, such as country, study design, setting, population, type of cancer, description of the intervention and control groups, outcomes, main conclusions and study limitations. Results and discussion A total of 874 records were identified, of which 11 satisfied the inclusion criteria. The studies were conducted mainly in the United States and included patients aged >50 years. Most studies had a before-after design. Pharmacist interventions primarily included educating and counselling patients on the management of adverse events. Rates of nausea and vomiting control, medication adherence and patient satisfaction were the most common outcome measures; a significant benefit in these parameters as a result of pharmacist interventions was noted in most studies. What is new and conclusion The findings from this systematic review indicate that pharmacist interventions can improve outcome measures in outpatients with cancer. However, the collective quality of the studies was poor and gaps identified indicate that further research is needed to provide more robust results. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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