The Validity of Predictive Equations to Estimate 24-Hour Sodium Excretion: The MESA and CARDIA Urinary Sodium Study.

We examined the population distribution of urinary sodium concentrations and the validity of existing equations predicting 24-hour sodium excretion from a single spot urine sample among older adults with and without hypertension. In 2013, 24-hour urine collections were obtained from 554 participants...

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Publicado en:American Journal of Epidemiology Vol. 186; no. 2; pp. 149 - 160
Autores principales: Allen, Norrina B., Lihui Zhao, Loria, Catherine M., Van Horn, Linda, Chia-Yih Wang, Pfeiffer, Christine M., Cogswell, Mary E., Wright, Jacqueline, Kiang Liu
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA 07/15/2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Oxford University Press / USA
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        10.1093/aje/kwx056
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        atl: The Validity of Predictive Equations to Estimate 24-Hour Sodium Excretion: The MESA and CARDIA Urinary Sodium Study.
      aug:
        au:
          Allen, Norrina B.
          Lihui Zhao
          Loria, Catherine M.
          Van Horn, Linda
          Chia-Yih Wang
          Pfeiffer, Christine M.
          Cogswell, Mary E.
          Wright, Jacqueline
          Kiang Liu
        affil: Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
      sug:
        subj:
          Predictive Value of Tests
          Predictive Validity
          Sodium Urine
          Hypertension
          Human
          Male
          Female
          Middle Age
          Aged
          Ethnic Groups
          Blood Pressure
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: We examined the population distribution of urinary sodium concentrations and the validity of existing equations predicting 24-hour sodium excretion from a single spot urine sample among older adults with and without hypertension. In 2013, 24-hour urine collections were obtained from 554 participants in the Multi-Ethnic Study of Atherosclerosis and the Coronary Artery Risk Development in Young Adults study, who were aged 45-79 years and of whom 56%were female, 58%were African American, and 54%had hypertension, in Chicago, Illinois. One-third provided a second 24-hour collection. Four timed (overnight, morning, afternoon, and evening) spot urine specimens and the 24-hour collection were analyzed for sodium and creatinine concentrations. Mean 24-hour sodium excretion was 3,926 (standard deviation (SD), 1,623) mg for white men, 2,480 (SD, 1,079) mg for white women, 3,454 (SD, 1,651)mg for African-Americanmen, and 3,397 (SD, 1,641)mg for African-American women, and did not differ significantly by hypertensive status.Mean bias (difference) in predicting 24-hour sodiumexcretion fromthe timed spot urine specimens ranged from -182 (95% confidence interval: -285, -79) to 1,090 (95% confidence interval: 966, 1,213) mg/day overall. Although the Tanaka equation using the evening specimen produced the least bias overall, no single equation worked well across subgroups of sex and race/ethnicity. A single spot urine sample is not a valid indicator of individual sodiumintake. New equations are needed to accurately estimate 24-hour sodiumexcretion for older adults.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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