MRI-TRUS fusion for electrode positioning during irreversible electroporation for treatment of prostate cancer.
We aimed to introduce an approach for image-guided positioning of electrodes for irreversible electroporation (IRE) in patients with prostate cancer using a magnetic resonance imaging-transrectal ultrasonography (MRI-TRUS) fusion technique. In 10 consecutive patients with biopsy-proven Gleason score...
| Publicado en: | Diagnostic & Interventional Radiology Vol. 23; no. 4; pp. 321 - 326 |
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| Autores principales: | , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Galenos Yayinevi Tic. LTD. STI
Jul/Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124217908&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124217908 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13053825 39NM jtl: Diagnostic & Interventional Radiology issn: 13053825 maglogo: N pubinfo: dt: Jul/Aug2017 vid: 23 iid: 4 pid: 28155 pub: Galenos Yayinevi Tic. LTD. STI artinfo: ui: 124217908 124217908 NLM28508759 10.5152/dir.2017.16276 NLM28508759 124217908 ppf: 321 ppct: 5 formats: fmt: @attributes: type: P tig: atl: MRI-TRUS fusion for electrode positioning during irreversible electroporation for treatment of prostate cancer. aug: au: Baur, Alexander D. J. Collettini, Federico Enders, Judith Maxeiner, Andreas Schreiter, Vera Stephan, Carsten Gebauer, Bernhard Hamm, Bernd Fischer, Thomas affil: Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany sug: subj: Prostatic Neoplasms Therapy Ultrasonography Methods Cytological Techniques Methods Electrodes Magnetic Resonance Imaging Methods Middle Age Prostatic Neoplasms Prostate Diagnostic Imaging Methods Male Aged Middle Aged: 45-64 years Aged: 65+ years Male ab: We aimed to introduce an approach for image-guided positioning of electrodes for irreversible electroporation (IRE) in patients with prostate cancer using a magnetic resonance imaging-transrectal ultrasonography (MRI-TRUS) fusion technique. In 10 consecutive patients with biopsy-proven Gleason score ≤3+4 prostate cancer, 19 G electrodes were inserted into the prostate using a transperineal access. Magnetic resonance images of the prostate acquired before IRE were fused with transrectal ultrasound images acquired during IRE. The position of the ultrasound probe was tracked via a sensor and corresponding magnetic resonance images were calculated in real-time. While MRI allowed delineation of the target volume, the position of the electrodes could be visualized on ultrasound images; the distance between individual electrode pairs was measured. Based on these measurements the software installed on the IRE unit was able to calculate the voltage necessary to generate the electric field for ablation. Using contrast-enhanced ultrasound, changes in perfusion within the ablation zone after IRE were documented. This technique allowed positioning of the electrodes around the target volume under image guidance in all patients treated with IRE. The target lesion and a safety margin were covered within the estimated ablation zone. MRI-TRUS guidance for IRE combines the advantages of good visualization of the target lesion on MRI with the ability of ultrasound to acquire imaging in real-time with a mobile device. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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