Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin.

Background: Epithelial-to-mesenchymal transition (EMT) is associated with downregulated E-cadherin and frequently with decreased proliferation. Proliferation may be restored in secondary metastases by mesenchymal-to-epithelial transition (MET). We tested whether E-cadherin maintains epithelial proli...

Descripción completa

Detalles Bibliográficos
Publicado en:Breast Cancer Research Vol. 19; pp. 1 - 26
Autores principales: Hugo, H. J., Gunasinghe, N. P. A. D., Hollier, B. G., Tanaka, T., Toh, T. Blick A., Hill, P., Gilles, C., Waltham, M., Thompson, E. W., Blick, T, Toh, A
Formato: Journal Article
Publicado: BioMed Central 7/27/2017
Acceso en línea:Ver este registro en EBSCOhost