Considerations in applying compressed sensing to in vivo phosphorus MR spectroscopic imaging of human brain at 3T.
The purpose of this study was to apply compressed sensing method for accelerated phosphorus MR spectroscopic imaging (31P-MRSI) of human brain in vivo at 3T. Fast 31P-MRSI data of five volunteers were acquired on a 3T clinical MR scanner using pulse-acquire sequence with a pseudorandom undersampling...
| Publicado en: | Medical & Biological Engineering & Computing Vol. 55; no. 8; pp. 1303 - 1316 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124485686&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124485686 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01400118 PO0 jtl: Medical & Biological Engineering & Computing issn: 01400118 maglogo: N pubinfo: dt: Aug2017 vid: 55 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 124485686 124485686 144032538 NLM27826817 124485686 10.1007/s11517-016-1591-9 NLM27826817 124485686 ppf: 1303 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Considerations in applying compressed sensing to in vivo phosphorus MR spectroscopic imaging of human brain at 3T. aug: au: Hatay, Gokce Yildirim, Muhammed Ozturk-Isik, Esin Hatay, Gokce Hale affil: Biomedical Engineering Institute , Bogazici University , Rasathane Cad, Kandilli Campus, Kandilli Mah. 34684 Istanbul Turkey sug: subj: Molecular Imaging Methods Image Processing, Computer Assisted Methods Brain Neoplasms Metabolism Magnetic Resonance Spectroscopy Methods Phosphorus Compounds Metabolism Phosphorus Pharmacokinetics Female Middle Age Male Signal Processing, Computer Assisted Human Sensitivity and Specificity Magnetic Resonance Imaging Methods Reproducibility of Results Validation Studies Comparative Studies Evaluation Research Multicenter Studies Middle Aged: 45-64 years Female Male ab: The purpose of this study was to apply compressed sensing method for accelerated phosphorus MR spectroscopic imaging (31P-MRSI) of human brain in vivo at 3T. Fast 31P-MRSI data of five volunteers were acquired on a 3T clinical MR scanner using pulse-acquire sequence with a pseudorandom undersampling pattern for a data reduction factor of 5.33 and were reconstructed using compressed sensing. Additionally, simulated 31P-MRSI human brain tumor datasets were created to analyze the effects of k-space sampling pattern, data matrix size, regularization parameters of the reconstruction, and noise on the compressed sensing accelerated 31P-MRSI data. The 31P metabolite peak ratios of the full and compressed sensing accelerated datasets of healthy volunteers in vivo were similar according to the results of a Bland-Altman test. The estimated effective spatial resolution increased with reduction factor and sampling more at the k-space center. A lower regularization parameter for both total variation and L1-norm penalties resulted in a better compressed sensing reconstruction of 31P-MRSI. Although the root-mean-square error increased with noise levels, the compressed sensing reconstruction was robust for up to a reduction factor of 10 for the simulated data that had sharply defined tumor borders. As a result, compressed sensing was successfully applied to accelerate 31P-MRSI of human brain in vivo at 3T. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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