Cerebrovascular pattern improved by ozone autohemotherapy: an entropy-based study on multiple sclerosis patients.

Ozone major autohemotherapy is effective in reducing the symptoms of multiple sclerosis (MS) patients, but its effects on brain are still not clear. In this work, we have monitored the changes in the cerebrovascular pattern of MS patients and normal subjects during major ozone autohemotherapy by usi...

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Publicado en:Medical & Biological Engineering & Computing Vol. 55; no. 8; pp. 1163 - 1176
Autores principales: Molinari, Filippo, Rimini, Daniele, Liboni, William, Acharya, U., Franzini, Marianno, Pandolfi, Sergio, Ricevuti, Giovanni, Vaiano, Francesco, Valdenassi, Luigi, Simonetti, Vincenzo, Acharya, U Rajendra
Formato: equations & formulas research tables/charts tracings Journal Article
Publicado: Springer Nature Aug2017
Acceso en línea:Ver este registro en EBSCOhost
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          Molinari, Filippo
          Rimini, Daniele
          Liboni, William
          Acharya, U.
          Franzini, Marianno
          Pandolfi, Sergio
          Ricevuti, Giovanni
          Vaiano, Francesco
          Valdenassi, Luigi
          Simonetti, Vincenzo
          Acharya, U Rajendra
        affil: Biolab, Department of Electronics and Telecommunications , Politecnico di Torino , Corso Duca degli Abruzzi 24 10129 Turin Italy
      sug:
        subj:
          Oxygen Consumption Drug Effects
          Multiple Sclerosis Therapy
          Brain Physiopathology
          Cerebrovascular Circulation Drug Effects
          Ozone Administration and Dosage
          Blood Flow Velocity Drug Effects
          Multiple Sclerosis Physiopathology
          Brain Mapping
          Physics
          Spectroscopy, Near-Infrared Methods
          Male
          Treatment Outcomes
          Adult
          Brain Drug Effects
          Female
          Clinical Assessment Tools
          Human
          Adult: 19-44 years
          Male
          Female
      ab: Ozone major autohemotherapy is effective in reducing the symptoms of multiple sclerosis (MS) patients, but its effects on brain are still not clear. In this work, we have monitored the changes in the cerebrovascular pattern of MS patients and normal subjects during major ozone autohemotherapy by using near-infrared spectroscopy (NIRS) as functional and vascular technique. NIRS signals are analyzed using a combination of time, time-frequency analysis and nonlinear analysis of intrinsic mode function signals obtained from empirical mode decomposition technique. Our results show that there is an improvement in the cerebrovascular pattern of all subjects indicated by increasing the entropy of the NIRS signals. Hence, we can conclude that the ozone therapy increases the brain metabolism and helps to recover from the lower activity levels which is predominant in MS patients.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
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        Journal Article
      ougenre: Article
    language: English
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