Microwave technology for detecting traumatic intracranial bleedings: tests on phantom of subdural hematoma and numerical simulations.

Traumatic brain injury is the leading cause of death and severe disability for young people and a major public health problem for elderly. Many patients with intracranial bleeding are treated too late, because they initially show no symptoms of severe injury and are not transported to a trauma cente...

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Published in:Medical & Biological Engineering & Computing Vol. 55; no. 8; pp. 1177 - 1189
Main Authors: Candefjord, Stefan, Winges, Johan, Malik, Ahzaz, Yu, Yinan, Rylander, Thomas, McKelvey, Tomas, Fhager, Andreas, Elam, Mikael, Persson, Mikael, Malik, Ahzaz Ahmad
Format: pictorial research tables/charts Journal Article
Published: Springer Nature Aug2017
Online Access:View this record in EBSCOhost
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      dt: Aug2017
      vid: 55
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s11517-016-1578-6
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        atl: Microwave technology for detecting traumatic intracranial bleedings: tests on phantom of subdural hematoma and numerical simulations.
      aug:
        au:
          Candefjord, Stefan
          Winges, Johan
          Malik, Ahzaz
          Yu, Yinan
          Rylander, Thomas
          McKelvey, Tomas
          Fhager, Andreas
          Elam, Mikael
          Persson, Mikael
          Malik, Ahzaz Ahmad
        affil: Department of Signals and Systems , Chalmers University of Technology , 412 96 Gothenburg Sweden
      sug:
        subj:
          Neuroradiography Methods
          Image Interpretation, Computer Assisted Methods
          Models, Biological
          Hematoma, Subdural Physiopathology
          Hematoma, Subdural Diagnosis
          Microwaves
          Computer Simulation
          Phantoms, Imaging
          Reproducibility of Results
          Sensitivity and Specificity
          Human
      ab: Traumatic brain injury is the leading cause of death and severe disability for young people and a major public health problem for elderly. Many patients with intracranial bleeding are treated too late, because they initially show no symptoms of severe injury and are not transported to a trauma center. There is a need for a method to detect intracranial bleedings in the prehospital setting. In this study, we investigate whether broadband microwave technology (MWT) in conjunction with a diagnostic algorithm can detect subdural hematoma (SDH). A human cranium phantom and numerical simulations of SDH are used. Four phantoms with SDH 0, 40, 70 and 110 mL are measured with a MWT instrument. The simulated dataset consists of 1500 observations. Classification accuracy is assessed using fivefold cross-validation, and a validation dataset never used for training. The total accuracy is 100 and 82-96 % for phantom measurements and simulated data, respectively. Sensitivity and specificity for bleeding detection were 100 and 96 %, respectively, for the simulated data. SDH of different sizes is differentiated. The classifier requires training dataset size in order of 150 observations per class to achieve high accuracy. We conclude that the results indicate that MWT can detect and estimate the size of SDH. This is promising for developing MWT to be used for prehospital diagnosis of intracranial bleedings.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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