Computer-aided diagnosis system for lung nodules based on computed tomography using shape analysis, a genetic algorithm, and SVM.

Lung cancer is the major cause of death among patients with cancer worldwide. This work is intended to develop a methodology for the diagnosis of lung nodules using images from the Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI). The proposed methodology uses image proce...

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Publicado en:Medical & Biological Engineering & Computing Vol. 55; no. 8; pp. 1129 - 1147
Autores principales: Carvalho Filho, Antonio, Silva, Aristófanes, Paiva, Anselmo, Nunes, Rodolfo, Gattass, Marcelo, de Carvalho Filho, Antonio Oseas, Silva, Aristófanes Corrêa, de Paiva, Anselmo Cardoso, Nunes, Rodolfo Acatauassú
Formato: diagnostic images equations & formulas pictorial research tables/charts Journal Article
Publicado: Springer Nature Aug2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
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        10.1007/s11517-016-1577-7
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        atl: Computer-aided diagnosis system for lung nodules based on computed tomography using shape analysis, a genetic algorithm, and SVM.
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          Carvalho Filho, Antonio
          Silva, Aristófanes
          Paiva, Anselmo
          Nunes, Rodolfo
          Gattass, Marcelo
          de Carvalho Filho, Antonio Oseas
          Silva, Aristófanes Corrêa
          de Paiva, Anselmo Cardoso
          Nunes, Rodolfo Acatauassú
        affil: Applied Computing Group - NCA , Federal University of Maranhão - UFMA , Av. dos Portugueses, SN, Campus do Bacanga, Bacanga São Luís 65085-580 Brazil
      sug:
        subj:
          Genetic Algorithms
          Solitary Pulmonary Nodule Pathology
          Tomography, X-Ray Computed Methods
          Solitary Pulmonary Nodule
          Radiographic Image Interpretation, Computer-Assisted Methods
          Information Science Methods
          Sensitivity and Specificity
          Radiographic Image Enhancement Methods
          Male
          Reproducibility of Results
          Models, Biological
          Female
          Middle Age
          Human
          Support Vector Machine
          Middle Aged: 45-64 years
          Male
          Female
      ab: Lung cancer is the major cause of death among patients with cancer worldwide. This work is intended to develop a methodology for the diagnosis of lung nodules using images from the Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI). The proposed methodology uses image processing and pattern recognition techniques. To differentiate the patterns of malignant and benign forms, we used a Minkowski functional, distance measures, representation of the vector of points measures, triangulation measures, and Feret diameters. Finally, we applied a genetic algorithm to select the best model and a support vector machine for classification. In the test stage, we applied the proposed methodology to 1405 (394 malignant and 1011 benign) nodules from the LIDC-IDRI database. The proposed methodology shows promising results for diagnosis of malignant and benign forms, achieving accuracy of 93.19 %, sensitivity of 92.75 %, and specificity of 93.33 %. The results are promising and demonstrate a good rate of correct detections using the shape features. Because early detection allows faster therapeutic intervention, and thus a more favorable prognosis for the patient, herein we propose a methodology that contributes to the area.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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