Pyoderma gangrenosum in a patient with chronic granulomatous disease: A case report.
Rationale: The simultaneous occurrence of pyoderma gangrenosum (PG) and chronic granulomatous disease (CGD) is uncommon and few cases have been reported worldwide.Patient Concerns: PG is a rare, chronic, ulcerative, neutrophilic skin disease of unknown etiology that requires immunosuppressive treatm...
| Publicado en: | Medicine Vol. 96; no. 31; pp. 1 - 7 |
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| Autores principales: | , , , , , , , |
| Formato: | case study Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
8/4/2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124566084&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124566084 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00257974 2S6 jtl: Medicine issn: 00257974 maglogo: N pubinfo: dt: 8/4/2017 vid: 96 iid: 31 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 124566084 124566084 NLM28767612 124566084 10.1097/MD.0000000000007718 NLM28767612 124566084 ppf: 1 ppct: 6 formats: tig: atl: Pyoderma gangrenosum in a patient with chronic granulomatous disease: A case report. aug: au: Nanoudis, Sideris Tsona, Afroditi Tsachouridou, Olga Morfesis, Petros Loli, Georgia Georgiou, Adamantini Zebekakis, Pantelis Metallidis, Symeon affil: 1st Department of Internal Medicine, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece. sug: subj: Granuloma Complications Pyoderma Gangrenosum Complications Ulcer Complications Pyoderma Gangrenosum Therapy Adult Ulcer Pathology Male Ulcer Therapy Granuloma Pathology Granuloma Therapy Ulcer Diagnosis Pyoderma Gangrenosum Pathology Granuloma Diagnosis Pyoderma Gangrenosum Diagnosis Diagnosis, Differential Adult: 19-44 years Male ab: Rationale: The simultaneous occurrence of pyoderma gangrenosum (PG) and chronic granulomatous disease (CGD) is uncommon and few cases have been reported worldwide.Patient Concerns: PG is a rare, chronic, ulcerative, neutrophilic skin disease of unknown etiology that requires immunosuppressive treatment. CGD belongs to Primary Immune Deficiencies in which the main defect lies in an inability of the phagocytic cells to generate superoxide making patients susceptible to serious, potentially life-threatening bacterial and fungal infections.Diagnoses: In this manuscript, we present a case of ulcerative pyoderma gangrenosum in a 28-year-old man with recent diagnosis of chronic granulomatous disease during hospitalization for resistant pulmonary tuberculosis complicated with Aspergillus infection.Interventions: Second-line therapy with dapsone and intravenous immunoglobulin was initially administered but eventually corticosteroids were added to treatment because of disease progression and further ulceration.Outcomes: Patient's ulcers were gradually healed with no side effects.Lessons: Corticosteroids could be used under close monitoring for the treatment of PG in a patient with CGD, despite the increased risk for infections. pubtype: Academic Journal doctype: case study Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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