Automated Classification of Lung Cancer Types from Cytological Images Using Deep Convolutional Neural Networks.

Lung cancer is a leading cause of death worldwide. Currently, in differential diagnosis of lung cancer, accurate classification of cancer types (adenocarcinoma, squamous cell carcinoma, and small cell carcinoma) is required. However, improving the accuracy and stability of diagnosis is challenging....

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Publicado en:BioMed Research International Vol. 2017; pp. 1 - 7
Autores principales: Teramoto, Atsushi, Tsukamoto, Tetsuya, Kiriyama, Yuka, Fujita, Hiroshi
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 8/13/2017
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: BioMed Research International
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      dt: 8/13/2017
      vid: 2017
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2017/4067832
        124587750
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        atl: Automated Classification of Lung Cancer Types from Cytological Images Using Deep Convolutional Neural Networks.
      aug:
        au:
          Teramoto, Atsushi
          Tsukamoto, Tetsuya
          Kiriyama, Yuka
          Fujita, Hiroshi
        affil: School of Health Sciences, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake City, Aichi 470-1192, Japan
      sug:
        subj:
          Automation
          Lung Neoplasms Classification
          Cytological Techniques
          Neural Networks (Computer)
          Human
          Diagnosis, Differential
          Lung Neoplasms Mortality
          Lung Neoplasms Diagnosis
          Adenocarcinoma
          Carcinoma, Squamous Cell
          Carcinoma, Small Cell Diagnosis
          Microscopy
          Diagnostic Imaging
          Databases
          Graphics
          Data Collection
          Funding Source
      ab: Lung cancer is a leading cause of death worldwide. Currently, in differential diagnosis of lung cancer, accurate classification of cancer types (adenocarcinoma, squamous cell carcinoma, and small cell carcinoma) is required. However, improving the accuracy and stability of diagnosis is challenging. In this study, we developed an automated classification scheme for lung cancers presented in microscopic images using a deep convolutional neural network (DCNN), which is a major deep learning technique. The DCNN used for classification consists of three convolutional layers, three pooling layers, and two fully connected layers. In evaluation experiments conducted, the DCNN was trained using our original database with a graphics processing unit. Microscopic images were first cropped and resampled to obtain images with resolution of 256 × 256 pixels and, to prevent overfitting, collected images were augmented via rotation, flipping, and filtering. The probabilities of three types of cancers were estimated using the developed scheme and its classification accuracy was evaluated using threefold cross validation. In the results obtained, approximately 71% of the images were classified correctly, which is on par with the accuracy of cytotechnologists and pathologists. Thus, the developed scheme is useful for classification of lung cancers from microscopic images.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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