The influence of interoceptive awareness on functional connectivity in patients with irritable bowel syndrome.
Irritable bowel syndrome (IBS) is characterized by visceral hypersensitivity likely related to altered processing of sensory stimuli along the brain-gut axis. Previous neuroimaging studies demonstrated structural and functional alteration of several brain areas involved in bodily representation, e.g...
| Publicado en: | Brain Imaging & Behavior Vol. 11; no. 4; pp. 1117 - 1129 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124638241&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124638241 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Aug2017 vid: 11 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 124638241 124638241 144150539 NLM27704405 10.1007/s11682-016-9595-5 NLM27704405 124638241 ppf: 1117 ppct: 12 formats: fmt: @attributes: type: P tig: atl: The influence of interoceptive awareness on functional connectivity in patients with irritable bowel syndrome. aug: au: Longarzo, Mariachiara Quarantelli, M. Aiello, M. Romano, M. Del Prete, A. Cimminiello, C. Cocozza, S. Olivo, G. Loguercio, C. Trojano, L. Grossi, D. affil: Department of Psychology , Second University of Naples , Viale Ellittico 31 Caserta Italy sug: subj: Perception Irritable Bowel Syndrome Psychosocial Factors Brain Physiopathology Irritable Bowel Syndrome Physiopathology Irritable Bowel Syndrome Aged Neural Pathways Physiopathology Young Adult Magnetic Resonance Imaging Brain Neuropsychological Tests Adult Brain Mapping Female Middle Age Male Cognition Neural Pathways Clinical Assessment Tools Scales Aged: 65+ years Adult: 19-44 years Middle Aged: 45-64 years Female Male ab: Irritable bowel syndrome (IBS) is characterized by visceral hypersensitivity likely related to altered processing of sensory stimuli along the brain-gut axis. Previous neuroimaging studies demonstrated structural and functional alteration of several brain areas involved in bodily representation, e.g. the insula, in patients with IBS. By means of resting-state functional magnetic resonance imaging (rs-fMRI) we searched for alteration of functional connectivity within the network involved in self-bodily consciousness. We found significant inverse correlation between hypochondriasis assessed through a clinical questionnaire and connectivity between posterior cingulate cortex and left supramarginal gyrus, extending into the adjacent superior temporal gyrus. Moreover, we observed a significant and positive correlation between a clinical questionnaire assessing interoception and connectivity between left anterior ventral insula and two clusters located in supramarginal gyrus bilaterally.Our findings highlight an "abnormal network synchrony" reflecting functional alteration, in the absence of structural and micro-structural changes, which might represent a possible therapeutic target for Irritable Bowel Syndrome. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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