Cortical time course of object naming investigated by repetitive navigated transcranial magnetic stimulation.
Human language organization models and language time course patterns are still predominantly derived from meta-analyses of numerous single publications, which only investigated scattered cortical regions. Moreover, there is not much literature available on the exact impact of repetitive navigated tr...
| Publicado en: | Brain Imaging & Behavior Vol. 11; no. 4; pp. 1192 - 1207 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Springer Nature
Aug2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124638256&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124638256 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Aug2017 vid: 11 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 124638256 124638256 NLM27448161 124638256 10.1007/s11682-016-9574-x NLM27448161 124638256 ppf: 1192 ppct: 15 formats: fmt: @attributes: type: P tig: atl: Cortical time course of object naming investigated by repetitive navigated transcranial magnetic stimulation. aug: au: Sollmann, Nico Ille, Sebastian Negwer, Chiara Boeckh-Behrens, Tobias Ringel, Florian Meyer, Bernhard Krieg, Sandro Krieg, Sandro M affil: Department of Radiology, Section of Neuroradiology, Klinikum rechts der Isar , Technische Universität München , Ismaninger Str. 22 81675 Munich Germany sug: subj: Visual Perception Physiology Cerebral Cortex Physiology Speech Physiology Brain Mapping Human Adult Transcranial Magnetic Stimulation Methods Neuropsychological Tests Female Male Magnetic Resonance Imaging Prospective Studies Validation Studies Comparative Studies Evaluation Research Multicenter Studies Impact of Events Scale Adult: 19-44 years Female Male ab: Human language organization models and language time course patterns are still predominantly derived from meta-analyses of numerous single publications, which only investigated scattered cortical regions. Moreover, there is not much literature available on the exact impact of repetitive navigated transcranial magnetic stimulation (rTMS) onset times on object naming. We, therefore, used a virtual lesion-based approach by mapping various cortical areas with rTMS to investigate the time course of object naming, and to specifically provide data on the pattern of rTMS language mapping results depending on different stimulation onset times. Ten healthy, right-handed subjects were enrolled, and rTMS in combination with an object-naming task was performed with different stimulation onset times (0 ms, 100 ms, 200 ms, 300 ms, 400 ms, and 500 ms). Subsequent to language mapping, all naming errors detected were systematically classified with respect to previous literature. The majority of errors was elicited within the opercular inferior frontal gyrus (opIFG) and ventral precentral gyrus (vPrG), and the spatial distribution of naming errors changed according to the time point of naming disruption by varying onset times. For instance, immediate rTMS onset led to a widespread cortical distribution of no responses, whereas performance and hesitation errors increased with higher stimulation onset times. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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