Prediction of pediatric HIV/AIDS survival in Nigeria using Naïve Bayes' Approach.

Data collected from 216 pediatric HIV/AIDS patients who were receiving antiretroviral drug treatment in Nigeria was used to develop a predictive model for HIV/AIDS survival based on identified variables. Interviews were conducted with the virologists and pediatricians to identify the variables predi...

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Publicado en:International Journal of Child Health & Human Development Vol. 10; no. 2; pp. 131 - 143
Autores principales: Idowu, Peter A., Aladekomo, Theophlus A., Agbelusi, Olutola, Alaba, Olumuyiwa B., Balogun, Jeremiah A.
Formato: equations & formulas research tables/charts Journal Article
Publicado: Nova Science Publishers, Inc. 2017
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Prediction of pediatric HIV/AIDS survival in Nigeria using Naïve Bayes' Approach.
      aug:
        au:
          Idowu, Peter A.
          Aladekomo, Theophlus A.
          Agbelusi, Olutola
          Alaba, Olumuyiwa B.
          Balogun, Jeremiah A.
        affil: Department of Computer Science and Engineering, Obafemi Awolowo University, Ile-Ife, Nigeria
      sug:
        subj:
          Opportunistic Infections
          Acquired Immunodeficiency Syndrome
          Viral Load
          AIDS Patients
          Nigeria
          Human
          ROC Curve
      ab: Data collected from 216 pediatric HIV/AIDS patients who were receiving antiretroviral drug treatment in Nigeria was used to develop a predictive model for HIV/AIDS survival based on identified variables. Interviews were conducted with the virologists and pediatricians to identify the variables predictive for HIV/AIDS survival in pediatric patients. 10-fold cross validation method was used in performing the stratification of the datasets collected into training and testing datasets following data preprocessing of the collected datasets. The model was formulated using the naïve Bayes' classifier -- a supervised machine learning algorithm based on Bayes' theory of conditional probability and simulated on the Waikato Environment for Knowledge Analysis (WEKA) using the identified variables, namely: CD4 count, viral load, opportunistic infection and the nutrition status of the pediatric patients involved in the study. The results showed 81.02% accuracy in the performance of the naïve Bayes' classifier used in developing the predictive model for HIV/AIDS survival in pediatric patients. In addition, the area under the receiver operating characteristics (ROC) curve had a value of 0.933 which showed how well the developed predictive model was able to discriminate between survived and nonsurvived cases. Model validation was performed by comparing the model results with that of historical data from two (2) selected tertiary institutions in Nigeria.
      pubtype: Academic Journal
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        research
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      ougenre: Article
    language: English
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