A pilot study of patient-centered outcome assessment using PROMIS for patients undergoing colorectal surgery.
Purpose: Few studies have assessed patient-reported outcomes following colorectal surgery. The absence of this information makes it difficult to inform patients about the near-term effects of surgery, beyond outcomes assessed by traditional clinical measures. This study was designed to provide infor...
| Publicado en: | Supportive Care in Cancer Vol. 25; no. 10; pp. 3103 - 3113 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124892783&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124892783 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09414355 O1J jtl: Supportive Care in Cancer issn: 09414355 maglogo: N pubinfo: dt: Oct2017 vid: 25 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 124892783 124892783 144165392 NLM28439726 124892783 10.1007/s00520-017-3718-4 NLM28439726 124892783 ppf: 3103 ppct: 10 formats: fmt: @attributes: type: P tig: atl: A pilot study of patient-centered outcome assessment using PROMIS for patients undergoing colorectal surgery. aug: au: Hedrick, Traci Harrigan, Amy Thiele, Robert Friel, Charles Kozower, Benjamin Stukenborg, George Hedrick, Traci L Harrigan, Amy M Thiele, Robert H Friel, Charles M Kozower, Benjamin D Stukenborg, George J affil: Department of Surgery , University of Virginia Health System , Charlottesville USA sug: subj: Surgery, Digestive System Rehabilitation Colorectal Neoplasms Rehabilitation Colorectal Neoplasms Surgery Outcome Assessment Male Depression Epidemiology Postoperative Complications Epidemiology Adult Quality of Life Aged Colorectal Neoplasms Psychosocial Factors Postoperative Period Middle Age Colorectal Neoplasms Epidemiology Pilot Studies Female Ferrans and Powers Quality of Life Index Impact of Events Scale Scales Social Readjustment Rating Scale Funding Source Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Male Female ab: Purpose: Few studies have assessed patient-reported outcomes following colorectal surgery. The absence of this information makes it difficult to inform patients about the near-term effects of surgery, beyond outcomes assessed by traditional clinical measures. This study was designed to provide information about the effects of colorectal surgery on physical, mental, and social well-being outcomes.Methods: The NIH Patient-Reported Outcomes Measurement Information System (PROMIS®) Assessment Center was used to collect patient responses prior to surgery and at their routine postoperative visit. Four domains were selected based on patient consultation and clinical experience: depression, pain interference, ability to participate in social roles and activities, and interest in sexual activity. Multilevel random coefficient models were used to assess the change in scores during the follow-up period and to assess the statistical significance of differences in trends over time associated with key clinical measures.Results: In total, 142 patients were consented, with 107 patients completing pre- and postoperative assessments (75%). Preoperative assessments were typically completed 1 month prior to surgery (mean 29.5 days before, SD = 19.7) and postoperative assessments 1 month after surgery (mean 30.7 days after, SD = 9.2), with a mean of 60.3 days between assessment dates. Patients demonstrated no statistically significant changes in scores for pain interference (-0.18 points, p = 0.80) or the ability to participate in social roles and activities (0.44 points, p = 0.55), but had significant decreases in depression scores between pre- and postoperative assessments (-1.6 points, p = 0.03) and near significant increases in scores for interest in sex (1.5 points, p = 0.06). Pain interference scores for patients with neoadjuvant chemotherapy significantly increased (3.5 points, p = 0.03). Scores for the interest in sex domain decreased (worsened) for patients with oncologic etiology (-3.7 points, p = 0.03). No other differences in score trends by patient characteristics were large enough to be statistically significant at the p < 0.05 threshold.Conclusion: These data suggest that the majority of patients quickly return to baseline physical, mental, and social function following colorectal surgery. This information can be used preoperatively to counsel patients about the typical impact of colorectal surgery on quality of life. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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