Is Contrast Enhanced Ultrasonography a useful tool in a beginner's hand? How much can a Computer Assisted Diagnosis prototype help in characterizing the malignancy of focal liver lesions?
Aim: Contrast enhanced ultrasound (CEUS) improved the characterization of focal liver lesions (FLLs), but is an operatordependent method. The goal of this paper was to test a computer assisted diagnosis (CAD) prototype and to see its benefit in assisting a beginner in the evaluation of FLLs.Material...
| Published in: | Medical Ultrasonography Vol. 19; no. 3; pp. 252 - 259 |
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| Main Authors: | , , , , , , , , , |
| Format: | Journal Article |
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Romanian Society of Ultrasonography in Medicine & Biology
Sep2017
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=124925729&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 124925729 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18444172 AX1S jtl: Medical Ultrasonography issn: 18444172 maglogo: N pubinfo: dt: Sep2017 vid: 19 iid: 3 pid: 57537 pub: Romanian Society of Ultrasonography in Medicine & Biology artinfo: ui: 124925729 124925729 NLM28845489 10.11152/mu-936 NLM28845489 124925729 ppf: 252 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Is Contrast Enhanced Ultrasonography a useful tool in a beginner's hand? How much can a Computer Assisted Diagnosis prototype help in characterizing the malignancy of focal liver lesions? aug: au: Moga, Tudor Voicu Popescu, Alina Sporea, Ioan Danila, Mirela David, Ciprian Guia, Vasile Iacob, Nicoleta Miclaus, Gratian Sirli, Roxana Gui, Vasile affil: Department of Gastroenterology and Hepatology, "Victor Babes" University of Medicine and Pharmacy, Timișoara, Romania sug: subj: Clinical Competence Statistics and Numerical Data Carcinoma, Hepatocellular Ultrasonography Methods Diagnosis, Computer Assisted Methods Liver Neoplasms Contrast Media Image Enhancement Methods Liver Reproducibility of Results Ferrans and Powers Quality of Life Index Scales ab: Aim: Contrast enhanced ultrasound (CEUS) improved the characterization of focal liver lesions (FLLs), but is an operatordependent method. The goal of this paper was to test a computer assisted diagnosis (CAD) prototype and to see its benefit in assisting a beginner in the evaluation of FLLs.Material and Method: Our cohort included 97 good quality CEUS videos[34% hepatocellular carcinomas (HCC), 12.3% hypervascular metastases (HiperM), 11.3% hypovascular metastases (HipoM), 24.7% hemangiomas (HMG), 17.5% focal nodular hyperplasia (FNH)] that were used to develop a CAD prototype based on an algorithm that tested a binary decision based classifier. Two young medical doctors (1 year CEUS experience), two experts and the CAD prototype, reevaluated 50 FLLs CEUS videos (diagnosis of benign vs. malignant) first blinded to clinical data, in order to evaluate the diagnostic gap beginner vs. expert.Results: The CAD classifier managed a 75.2% overall (benign vs. malignant) correct classification rate. The overall classification rates for the evaluators, before and after clinical data were: first beginner-78%; 94%; second beginner-82%; 96%; first expert-94%; 100%; second expert-96%; 98%. For both beginners, the malignant vs. benign diagnosis significantly improved after knowing the clinical data (p=0.005; p=0,008). The expert was better than the beginner (p=0.04) and better than the CAD (p=0.001). CAD in addition to the beginner can reach the expert diagnosis.Conclusions: The most frequent lesions misdiagnosed at CEUS were FNH and HCC. The CAD prototype is a good comparing tool for a beginner operator that can be developed to assist the diagnosis. In order to increase the classification rate, the CAD system for FLL in CEUS must integrate the clinical data. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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