An evaluation of the BrainLAB 6D ExacTrac/Novalis Tx System for image-guided intracranial radiotherapy.

PurposeStereotactic-fractionated radiotherapy and radiosurgery (RS) for benign and malignant intracranial lesions relies on a very high degree of accuracy in dose alignment due to the ablative dose delivered, and therefore requires a high-precision image guidance modality. The aim of this review is...

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Publicado en:Journal of Radiotherapy in Practice Vol. 16; no. 3; pp. 326 - 334
Autores principales: Montgomery, Claire, Collins, Mark
Formato: pictorial research Journal Article
Publicado: Cambridge University Press Sep2017
Acceso en línea:Ver este registro en EBSCOhost
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        14603969
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      dt: Sep2017
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      pub: Cambridge University Press
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        10.1017/S1460396917000139
        124973344
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        atl: An evaluation of the BrainLAB 6D ExacTrac/Novalis Tx System for image-guided intracranial radiotherapy.
      aug:
        au:
          Montgomery, Claire
          Collins, Mark
        affil: Edinburgh Cancer Centre, Western General Hospital, Edinburgh, UK
      sug:
        subj:
          Brain Neoplasms Surgery
          Brain Neoplasms Radiography
          Surgery, Computer-Assisted Methods
          Radiosurgery Methods
          Tomography, X-Ray Computed Methods
          Radiotherapy, Computer-Assisted Methods
          Human
          Validity
          Patient Positioning
          Algorithms
          Radiation Dosage
          Radiotherapy, Conformal
          Stereotaxic Techniques Methods
          Rotation
      ab: PurposeStereotactic-fractionated radiotherapy and radiosurgery (RS) for benign and malignant intracranial lesions relies on a very high degree of accuracy in dose alignment due to the ablative dose delivered, and therefore requires a high-precision image guidance modality. The aim of this review is to investigate the localisation and verification accuracy performance of ExacTrac (ET) and Novalis Tx System.Materials and methodsA systematic review of the database Science Direct was carried out using search terms ‘stereotactic radiotherapy (SRT)’ and ‘ET’. All articles before 2000 were excluded. Only articles that involved intracranial lesions, with the exception of one article, were included in the final review.ResultsResults from gold standard Hidden Target Tests and patient data show that patient position can be reproduced within 1·0 mm with the use of ET imaging. In addition, the 6 degrees of freedom algorithm function of ET allows for better translational accuracy as well optimal positioning when rotations are corrected for. Studies showed excellent correlation (p<0·01) between bony ET images and cone beam computed tomography (CBCT) soft tissue registration, evidencing the safe reliance of bony anatomy for image guidance via ET. Shifts were found to be comparable between CBCT and ET.ConclusionThere is the need for regular calibration to prevent systematic errors and potential geographic miss. However, due to ET’s additional benefits, including reduced concomitant dose and faster imaging time, ET is the superior image guidance modality for RS/SRT in the treatment of intracranial lesions.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        Journal Article
      ougenre: Article
    language: English
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