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Cryptococcal Infection in Transplant Kidney Manifesting as Chronic Allograft Dysfunction.

Invasive fungal infections (IFIs) are a significant cause of morbidity in solid organ transplant (SOT) recipients. Common causes among them are Aspergillus, Candida, and Cryptococcus. Antifungal prophylaxis has led to decrease in overall incidence of IFI; however, there is very little decline in the...

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Published in:Indian Journal of Nephrology Vol. 27; no. 5; pp. 392 - 395
Main Authors: Agrawal, C., Sood, V., Kumar, A., Raghavan, V.
Format: case study pictorial Journal Article
Published: Scientific Scholar LLC Sep/Oct2017
Online Access:View this record in EBSCOhost
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      jtl: Indian Journal of Nephrology
      issn: 09714065
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      dt: Sep/Oct2017
      vid: 27
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      pub: Scientific Scholar LLC
      place: Pittsford, New York
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        atl: Cryptococcal Infection in Transplant Kidney Manifesting as Chronic Allograft Dysfunction.
      aug:
        au:
          Agrawal, C.
          Sood, V.
          Kumar, A.
          Raghavan, V.
        affil: Department of Internal Medical, Armed Forces Medical College, Pune, Maharashtra, India
      sug:
        subj:
          Kidney Transplantation
          Cryptococcus
          Graft Rejection
          Mycoses Diagnosis
          Allografts
          Mycoses Complications
          Male
          Adult
          Transplant Recipients
          Biopsy
          Adult: 19-44 years
          Male
      ab: Invasive fungal infections (IFIs) are a significant cause of morbidity in solid organ transplant (SOT) recipients. Common causes among them are Aspergillus, Candida, and Cryptococcus. Antifungal prophylaxis has led to decrease in overall incidence of IFI; however, there is very little decline in the incidence of Cryptococcal infections of SOT recipients because effective prophylaxis is not available against this infectious agent. Spectrum of manifestation of Cryptococcal infection varies in immunocompetent and immunocompromised host with subclinical and self-limiting with lungs being the primary site in immunocompetent and central nervous system as the most common site in an immunocompromised host. Other preferred sites are cutaneous, pulmonary, urinary tract (prostate) and the bone. Herein, we describe a young adult renal transplant recipient male diagnosed as a rare case of biopsy proven Cryptococcal infection in transplant kidney manifesting as chronic allograft dysfunction.
      pubtype: Academic Journal
      doctype:
        case study
        pictorial
        Journal Article
      ougenre: Article
    language: English
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