Classification of Focal and Non Focal Epileptic Seizures Using Multi-Features and SVM Classifier.

Identifying epileptogenic zones prior to surgery is an essential and crucial step in treating patients having pharmacoresistant focal epilepsy. Electroencephalogram (EEG) is a significant measurement benchmark to assess patients suffering from epilepsy. This paper investigates the application of mul...

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Published in:Journal of Medical Systems Vol. 41; no. 10; pp. 1 - 15
Main Authors: Sriraam, N., Raghu, S.
Format: equations & formulas research tables/charts tracings Journal Article
Published: Springer Nature Oct2017
Online Access:View this record in EBSCOhost
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      dt: Oct2017
      vid: 41
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-017-0800-x
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        atl: Classification of Focal and Non Focal Epileptic Seizures Using Multi-Features and SVM Classifier.
      aug:
        au:
          Sriraam, N.
          Raghu, S.
        affil: Center for Medical Electronics and Computing , Ramaiah Institute of Technology (Affiliated to VTU Belgaum) , Bangalore 560054 India
      sug:
        subj:
          Seizures Classification
          Electroencephalography
          Signal Processing, Computer Assisted
          Human
          Wilcoxon Rank Sum Test
          P-Value
          Data Analysis, Computer Assisted
      ab: Identifying epileptogenic zones prior to surgery is an essential and crucial step in treating patients having pharmacoresistant focal epilepsy. Electroencephalogram (EEG) is a significant measurement benchmark to assess patients suffering from epilepsy. This paper investigates the application of multi-features derived from different domains to recognize the focal and non focal epileptic seizures obtained from pharmacoresistant focal epilepsy patients from Bern Barcelona database. From the dataset, five different classification tasks were formed. Total 26 features were extracted from focal and non focal EEG. Significant features were selected using Wilcoxon rank sum test by setting p-value ( p < 0.05) and z-score (−1.96 > z > 1.96) at 95% significance interval. Hypothesis was made that the effect of removing outliers improves the classification accuracy. Turkey's range test was adopted for pruning outliers from feature set. Finally, 21 features were classified using optimized support vector machine (SVM) classifier with 10-fold cross validation. Bayesian optimization technique was adopted to minimize the cross-validation loss. From the simulation results, it was inferred that the highest sensitivity, specificity, and classification accuracy of 94.56%, 89.74%, and 92.15% achieved respectively and found to be better than the state-of-the-art approaches. Further, it was observed that the classification accuracy improved from 80.2% with outliers to 92.15% without outliers. The classifier performance metrics ensures the suitability of the proposed multi-features with optimized SVM classifier. It can be concluded that the proposed approach can be applied for recognition of focal EEG signals to localize epileptogenic zones.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        tracings
        Journal Article
      ougenre: Article
    language: English
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