RNA sequencing of esophageal adenocarcinomas identifies novel fusion transcripts, including NPC1-MELK, arising from a complex chromosomal rearrangement.

Background: Studies of chromosomal rearrangements and fusion transcripts have elucidated mechanisms of tumorigenesis and led to targeted cancer therapies. This study was aimed at identifying novel fusion transcripts in esophageal adenocarcinoma (EAC).Methods: To identify new fusion transcripts assoc...

Full description

Bibliographic Details

Published in:	Cancer (0008543X) Vol. 123; no. 20; pp. 3916 - 3926
Main Authors:	Wang, Zhixiong, Cheng, Yulan, Abraham, John M., Yan, Rong, Liu, Xi, Chen, Wei, Ibrahim, Sariat, Schroth, Gary P., Ke, Xiquan, He, Yulong, Meltzer, Stephen J.
Format:	research tables/charts Journal Article
Published:	Wiley-Blackwell Oct2017
Online Access:	View this record in EBSCOhost