Comparison of biochemical parameters of blood and urine in spinal cord injury patients and association with urinary stone formation.

OBJECTIVE: The aim of this study was to compare the biochemical parameters of the urine and blood in spinal cord injury (SCI) patients and healthy subjects. METHODS: Thirty male patients with SCI were enrolled. Biochemical features of the urine and blood of the SCI patients were compared to healthy...

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Published in:Journal of Back & Musculoskeletal Rehabilitation Vol. 30; no. 5; pp. 1111 - 1116
Main Authors: Aydin, Gülümser, Demir, S. Özbudak, Ekiz, Timur, Inanir, Murat, Tosun, Aliye
Format: research tables/charts Journal Article
Published: Sage Publications Inc. 2017
Online Access:View this record in EBSCOhost
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        10538127
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      jtl: Journal of Back & Musculoskeletal Rehabilitation
      issn: 10538127
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      dt: 2017
      vid: 30
      iid: 5
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        125469771
        125469771
        125469771
        10.3233/BMR-169747
        125469771
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        atl: Comparison of biochemical parameters of blood and urine in spinal cord injury patients and association with urinary stone formation.
      aug:
        au:
          Aydin, Gülümser
          Demir, S. Özbudak
          Ekiz, Timur
          Inanir, Murat
          Tosun, Aliye
        affil: Department of Physical Medicine and Rehabilitation, Yıldırım Beyazıt University Faculty of Medicine, Ankara, Turkey
      sug:
        subj:
          Biochemical Phenomena
          Blood
          Urine
          Spinal Cord Injuries
          Urinary Calculi Prevention and Control
          Human
          Male
          X-Rays Methods
          Descriptive Statistics
          Adult
          Kidney
          Bladder
          Urinary Calculi Diagnosis
          Urinalysis
          Bacterial Infections
          Citrates
          Magnesium
          Calcium
          Metabolism
          Urinary Tract Infections
          Adult: 19-44 years
          Male
      ab: OBJECTIVE: The aim of this study was to compare the biochemical parameters of the urine and blood in spinal cord injury (SCI) patients and healthy subjects. METHODS: Thirty male patients with SCI were enrolled. Biochemical features of the urine and blood of the SCI patients were compared to healthy subjects. Extracted stones were analyzed by X-ray diffraction. RESULTS: A total of 30 patients with SCI (mean age of 28.77 ± 7.3 years) and 10 healthy subjects (mean age of 27.6 + 6.2 years) were included. Among the patients with SCI; 12 of them (40%) had urinary stones and 18 of them (60%) did not. Urinary stone was localized in the kidneys and bladder in 25% and 75% of the subjects, respectively. The mean duration of cord injury at diagnosis of urinary stone was 9.2 ± 6 months. Urine cultures obtained on admission were negative for the control group, while the microorganism isolation rate was 73.3% in the SCI group. The urinary excretion of citrate and Mg were lower in the patient group compared with control group (p = 0.008, p = 0.001, respectively). As for the diffraction analysis of eight stones; five (62.5%) of the stones were calcium oxalate, two (25%) of them were calcium phosphate, and one (12.5%) was magnesium ammonium phosphate. CONCLUSION: Both infection and metabolic changes play an important role in stones formation in SCI patients. The urinary excretion of citrate and Mg was decreased and urinary PH was increased in SCI patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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