Capillary blood for point-of-care testing.

Clinically, blood sample analysis has been widely used for health monitoring. In hospitals, arterial and venous blood are utilized to detect various disease biomarkers. However, collection methods are invasive, painful, may result in injury and contamination, and skilled workers are required, making...

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Publicado en:Critical Reviews in Clinical Laboratory Sciences Vol. 54; no. 5; pp. 294 - 309
Autores principales: Tang, Ruihua, Yang, Hui, Choi, Jane Ru, Gong, Yan, You, MinLi, Wen, Ting, Li, Ang, Li, XiuJun, Xu, Bo, Zhang, Sufeng, Mei, Qibing, Xu, Feng
Formato: pictorial review tables/charts Journal Article
Publicado: Taylor & Francis Ltd Aug2017
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Taylor & Francis Ltd
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        atl: Capillary blood for point-of-care testing.
      aug:
        au:
          Tang, Ruihua
          Yang, Hui
          Choi, Jane Ru
          Gong, Yan
          You, MinLi
          Wen, Ting
          Li, Ang
          Li, XiuJun
          Xu, Bo
          Zhang, Sufeng
          Mei, Qibing
          Xu, Feng
        affil: School of Life Sciences, Northwestern Polytechnical University, Xi'an, P.R. China
      sug:
        subj:
          Blood Specimen Collection Methods
          Capillaries
          Point-of-Care Testing
          Monitoring, Physiologic
          Technology, Medical
          Blood Specimen Collection Equipment and Supplies
          Microfluidic Analytical Techniques
          Funding Source
          Blood Gas Analysis
          Electrolytes Analysis
          Hematologic Tests
          Blood Glucose Analysis
      ab: Clinically, blood sample analysis has been widely used for health monitoring. In hospitals, arterial and venous blood are utilized to detect various disease biomarkers. However, collection methods are invasive, painful, may result in injury and contamination, and skilled workers are required, making these methods unsuitable for use in a resource-limited setting. In contrast, capillary blood is easily collected by a minimally invasive procedure and has excellent potential for use in point-of-care (POC) health monitoring. In this review, we first discuss the differences among arterial blood, venous blood, and capillary blood in terms of the puncture sites, components, sample volume, collection methods, and application areas. Additionally, we review the most recent advances in capillary blood-based commercial products and microfluidic instruments for various applications. We also compare the accuracy of microfluidic-based testing with that of laboratory-based testing for capillary blood-based disease diagnosis at the POC. Finally, we discuss the challenges and future perspectives for developing capillary blood-based POC instruments.
      pubtype: Academic Journal
      doctype:
        pictorial
        review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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