Whole-tumor histogram analysis of the cerebral blood volume map: tumor volume defined by 11C-methionine positron emission tomography image improves the diagnostic accuracy of cerebral glioma grading.
Purpose: This study aimed to compare the tumor volume definition using conventional magnetic resonance (MR) and 11C-methionine positron emission tomography (MET/PET) images in the differentiation of the pre-operative glioma grade by using whole-tumor histogram analysis of normalized cerebral blood v...
| Publicado en: | Japanese Journal of Radiology Vol. 35; no. 10; pp. 613 - 622 |
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| Autores principales: | , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125581009&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 125581009 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 18671071 AUCM jtl: Japanese Journal of Radiology issn: 18671071 maglogo: N pubinfo: dt: Oct2017 vid: 35 iid: 10 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 125581009 125581009 143906400 NLM28879406 125581009 10.1007/s11604-017-0675-2 NLM28879406 125581009 ppf: 613 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Whole-tumor histogram analysis of the cerebral blood volume map: tumor volume defined by 11C-methionine positron emission tomography image improves the diagnostic accuracy of cerebral glioma grading. aug: au: Wu, Rongli Watanabe, Yoshiyuki Arisawa, Atsuko Takahashi, Hiroto Tanaka, Hisashi Fujimoto, Yasunori Watabe, Tadashi Isohashi, Kayako Hatazawa, Jun Tomiyama, Noriyuki affil: Department of Diagnostic and Interventional Radiology , Osaka University Graduate School of Medicine , 2-2 Yamadaoka Suita 565-0871 Japan sug: subj: Brain Neoplasms Glioma Glioma Pathology Tomography, Emission-Computed Methods Brain Neoplasms Pathology Female Brain Mapping Methods Reproducibility of Results Brain Aged Male Glioma Blood Supply Neoplasm Grading Middle Age Aged, 80 and Over Young Adult Brain Pathology Radioisotopes Methionine Brain Neoplasms Blood Supply Body Weights and Measures Magnetic Resonance Imaging Methods Adult Human Aged: 65+ years Middle Aged: 45-64 years Aged, 80 & over Adult: 19-44 years Female Male ab: Purpose: This study aimed to compare the tumor volume definition using conventional magnetic resonance (MR) and 11C-methionine positron emission tomography (MET/PET) images in the differentiation of the pre-operative glioma grade by using whole-tumor histogram analysis of normalized cerebral blood volume (nCBV) maps.Materials and Methods: Thirty-four patients with histopathologically proven primary brain low-grade gliomas (n = 15) and high-grade gliomas (n = 19) underwent pre-operative or pre-biopsy MET/PET, fluid-attenuated inversion recovery, dynamic susceptibility contrast perfusion-weighted magnetic resonance imaging, and contrast-enhanced T1-weighted at 3.0 T. The histogram distribution derived from the nCBV maps was obtained by co-registering the whole tumor volume delineated on conventional MR or MET/PET images, and eight histogram parameters were assessed.Results: The mean nCBV value had the highest AUC value (0.906) based on MET/PET images. Diagnostic accuracy significantly improved when the tumor volume was measured from MET/PET images compared with conventional MR images for the parameters of mean, 50th, and 75th percentile nCBV value (p = 0.0246, 0.0223, and 0.0150, respectively).Conclusion: Whole-tumor histogram analysis of CBV map provides more valuable histogram parameters and increases diagnostic accuracy in the differentiation of pre-operative cerebral gliomas when the tumor volume is derived from MET/PET images. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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