Numerical activities of daily living in adults with neurofibromatosis type 1.

Background This study aimed to identify the mathematical domains affected in adults with neurofibromatosis 1 (NF1) and the impact of the numerical difficulties on the patients' activities of daily living. Methods We assessed 28 adult patients with NF1 and 28 healthy control participants. All partici...

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Publicado en:Journal of Intellectual Disability Research Vol. 61; no. 11; pp. 1069 - 1078
Autores principales: Burgio, F., Benavides‐Varela, S., Arcara, G., Trevisson, E., Frizziero, D., Clementi, M., Semenza, C.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2017
      vid: 61
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jir.12408
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        atl: Numerical activities of daily living in adults with neurofibromatosis type 1.
      aug:
        au:
          Burgio, F.
          Benavides‐Varela, S.
          Arcara, G.
          Trevisson, E.
          Frizziero, D.
          Clementi, M.
          Semenza, C.
        affil: San Camillo Hospital IRCCS, Venice Italy
      sug:
        subj:
          Activities of Daily Living Evaluation
          Mathematics Utilization
          Neurofibromatosis 1 Complications
          Psychological Tests
          T-Tests
          Adaptation, Psychological
          Competency Assessment
          Cognition Evaluation
          Human
          Male
          Female
          Young Adult
          Adult
          Middle Age
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background This study aimed to identify the mathematical domains affected in adults with neurofibromatosis 1 (NF1) and the impact of the numerical difficulties on the patients' activities of daily living. Methods We assessed 28 adult patients with NF1 and 28 healthy control participants. All participants completed the standardised battery of numerical activities of daily living along with clinical batteries of cognitive (Mini-Mental State Examination) and daily functioning (instrumental activities of daily living). The group comparisons of the performance on numerical activities of daily living were carried out using t-test correcting for multiple comparisons. Results The results showed that the NF1 group performed worse than controls in written subtractions, written multiplication, multiplication principles and digit comprehension (dot counting) tasks. Importantly, no significant differences in numerical ecological tasks were found between patients and controls, suggesting a possible use of compensatory strategies in daily living abilities in spite of calculation deficits. Conclusion The findings indicate that NF1 affects calculation but not the basic comprehension or representation of numbers in adult patients. These data have important implications for designing cognitive interventions tailored to the cognitive profile of individuals with NF1.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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