Zinc-Containing Hydroxyapatite Enhances Cold-Light-Activated Tooth Bleaching Treatment In Vitro.

Cold-light bleaching treatment has grown to be a popular tooth whitening procedure in recent years, but its side effect of dental enamel demineralization is a widespread problem. The aim of this study was to synthesize zinc-substituted hydroxyapatite as an effective biomaterial to inhibit deminerali...

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Publicado en:BioMed Research International Vol. 2017; pp. 1 - 11
Autores principales: Li, Yi, Shi, Xinchang, Li, Wei
Formato: research tables/charts tracings Journal Article
Publicado: Wiley-Blackwell 10/12/2017
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 10/12/2017
      vid: 2017
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2017/6261248
        125621966
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        atl: Zinc-Containing Hydroxyapatite Enhances Cold-Light-Activated Tooth Bleaching Treatment In Vitro.
      aug:
        au:
          Li, Yi
          Shi, Xinchang
          Li, Wei
        affil: State Key Laboratory of Oral Diseases, Chengdu 610041, China
      sug:
        subj:
          Hydroxyapatites
          Zinc
          Tooth Bleaching Methods
          Human
          Dentistry
          Dental Care
          Luminescent Measurements
          Cold
          Dental Enamel
          Tooth Demineralization Diagnosis
          Tooth Demineralization Prevention and Control
          Biocompatible Materials
          X-Rays
          Biological Assay
      ab: Cold-light bleaching treatment has grown to be a popular tooth whitening procedure in recent years, but its side effect of dental enamel demineralization is a widespread problem. The aim of this study was to synthesize zinc-substituted hydroxyapatite as an effective biomaterial to inhibit demineralization or increase remineralization. We synthesized zinc-substituted hydroxyapatite containing different zinc concentrations and analysed the product using X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, and energy dispersive spectrometer (EDS). The biological assessment of Zn-HA was conducted by CCK-8 assay and bacterial inhibition tests. pH cycling was performed to estimate the effect of Zn-HA on the enamel surface after cold-light bleaching treatment. The XRD, FTIR, and EDS results illustrated that zinc ions and hydroxyapatite combined in two forms: (1) Zn2+ absorbed on the surface of HA crystal and (2) Zn2+ incorporated into the lattice of HA. The results indicated that 2% Zn-HA, 4% Zn-HA, and 8% Zn-HA effectively inhibited the growth of bacteria yet showed poor biocompatibility, whereas 1% Zn-HA positively affected osteoblast proliferation. The XRD and scanning electron microscopy (SEM) results showed that the use of Zn-HA in pH cycling is obviously beneficial for enamel remineralization. Zinc-substituted hydroxyapatite could be a promising biomaterial for use in cold-light bleaching to prevent enamel demineralization.
      pubtype: Academic Journal
      doctype:
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    language: English
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