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Multiparametric magnetic resonance imaging for transition zone prostate cancer: essential findings, limitations, and future directions.

Objective: Review the multiparametric MRI (mpMRI) findings of transition zone (TZ) prostate cancer (PCa) using T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) MRI and to integrate mpMRI findings with clinical history, laboratory values, and histopath...

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Published in:Abdominal Radiology Vol. 42; no. 11; pp. 2732 - 2745
Main Authors: Lewis, Sara, Besa, Cecilia, Rosen, Ally, Rastinehad, Ardeshir, Semaan, Sahar, Hectors, Stefanie, Taouli, Bachir
Format: Journal Article
Published: Springer Nature Nov2017
Online Access:View this record in EBSCOhost
Summary:Objective: Review the multiparametric MRI (mpMRI) findings of transition zone (TZ) prostate cancer (PCa) using T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) MRI and to integrate mpMRI findings with clinical history, laboratory values, and histopathology. Conclusion: TZ prostate tumors are challenging to detect clinically and at MRI. mpMRI using the combination of sequences has the potential to improve accuracy of TZ cancer detection and staging.