Topical Medical Cannabis: A New Treatment for Wound Pain-Three Cases of Pyoderma Gangrenosum.
Pain associated with integumentary wounds is highly prevalent, yet it remains an area of significant unmet need within health care. Currently, systemically administered opioids are the mainstay of treatment. However, recent publications are casting opioids in a negative light given their high side e...
| Published in: | Journal of Pain & Symptom Management Vol. 54; no. 5; pp. 732 - 737 |
|---|---|
| Main Authors: | , |
| Format: | case study Journal Article |
| Published: |
Elsevier B.V.
Nov2017
|
| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125782178&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 125782178 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08853924 4CB jtl: Journal of Pain & Symptom Management issn: 08853924 maglogo: N pubinfo: dt: Nov2017 vid: 54 iid: 5 pid: 467 pub: Elsevier B.V. place: New York, New York artinfo: ui: 125782178 125782178 NLM28818631 125782178 10.1016/j.jpainsymman.2017.06.005 NLM28818631 125782178 ppf: 732 ppct: 5 formats: tig: atl: Topical Medical Cannabis: A New Treatment for Wound Pain-Three Cases of Pyoderma Gangrenosum. aug: au: Maida, Vincent Corban, Jason affil: University of Toronto, Toronto, Ontario, Canada sug: subj: Analgesics, Nonnarcotic Administration and Dosage Pyoderma Gangrenosum Drug Therapy Medical Marijuana Administration and Dosage Wounds and Injuries Drug Therapy Pain Drug Therapy Female Wounds and Injuries Physiopathology Pyoderma Gangrenosum Physiopathology Pyoderma Gangrenosum Pathology Pain Physiopathology Male Leg Aged Wounds and Injuries Pathology Administration, Topical Middle Age Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Pain associated with integumentary wounds is highly prevalent, yet it remains an area of significant unmet need within health care. Currently, systemically administered opioids are the mainstay of treatment. However, recent publications are casting opioids in a negative light given their high side effect profile, inhibition of wound healing, and association with accidental overdose, incidents that are frequently fatal. Thus, novel analgesic strategies for wound-related pain need to be investigated. The ideal methods of pain relief for wound patients are modalities that are topical, lack systemic side effects, noninvasive, self-administered, and display rapid onset of analgesia. Extracts derived from the cannabis plant have been applied to wounds for thousands of years. The discovery of the human endocannabinoid system and its dominant presence throughout the integumentary system provides a valid and logical scientific platform to consider the use of topical cannabinoids for wounds. We are reporting a prospective case series of three patients with pyoderma gangrenosum that were treated with topical medical cannabis compounded in nongenetically modified organic sunflower oil. Clinically significant analgesia that was associated with reduced opioid utilization was noted in all three cases. Topical medical cannabis has the potential to improve pain management in patients suffering from wounds of all classes. pubtype: Academic Journal doctype: case study Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|