Mapping temporo-parietal and temporo-occipital cortico-cortical connections of the human middle longitudinal fascicle in subject-specific, probabilistic, and stereotaxic Talairach spaces.
Originally, the middle longitudinal fascicle (MdLF) was defined as a long association fiber tract connecting the superior temporal gyrus and temporal pole with the angular gyrus. More recently its description has been expanded to include all long postrolandic cortico-cortical association connections...
| Publicado en: | Brain Imaging & Behavior Vol. 11; no. 5; pp. 1258 - 1278 |
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| Autores principales: | , , , , , , , , , , , , , , |
| Formato: | diagnostic images pictorial research tables/charts Journal Article |
| Publicado: |
Springer Nature
Oct2017
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=125839900&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 125839900 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 19317557 3GSC jtl: Brain Imaging & Behavior issn: 19317557 maglogo: N pubinfo: dt: Oct2017 vid: 11 iid: 5 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 125839900 125839900 144136665 NLM27714552 125839900 10.1007/s11682-016-9589-3 NLM27714552 125839900 ppf: 1258 ppct: 20 formats: fmt: @attributes: type: P tig: atl: Mapping temporo-parietal and temporo-occipital cortico-cortical connections of the human middle longitudinal fascicle in subject-specific, probabilistic, and stereotaxic Talairach spaces. aug: au: Makris, Nikos Zhu, A. Papadimitriou, G. Mouradian, P. Ng, I. Scaccianoce, E. Baselli, G. Baglio, F. Shenton, M. Rathi, Y. Dickerson, B. Yeterian, E. Kubicki, M. Papadimitriou, G M Shenton, M E affil: Departments of Psychiatry and Neurology Services, Center for Morphometric Analysis, Center for Neural Systems Investigations, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital , Harvard Medical School , Building 149, 13th Street, Charlestown Boston 02129 USA sug: subj: Brain Anatomy and Histology Occipital Lobe Anatomy and Histology Temporal Lobe Anatomy and Histology Parietal Lobe Anatomy and Histology Magnetic Resonance Imaging Methods Brain Adult Female Temporal Lobe Adolescence Middle Age Young Adult Neural Pathways Anatomy and Histology Parietal Lobe Male Occipital Lobe Neural Pathways Body Weights and Measures Funding Source Human Adult: 19-44 years Adolescent: 13-18 years Middle Aged: 45-64 years Female Male ab: Originally, the middle longitudinal fascicle (MdLF) was defined as a long association fiber tract connecting the superior temporal gyrus and temporal pole with the angular gyrus. More recently its description has been expanded to include all long postrolandic cortico-cortical association connections of the superior temporal gyrus and dorsal temporal pole with the parietal and occipital lobes. Despite its location and size, which makes MdLF one of the most prominent cerebral association fiber tracts, its discovery in humans is recent. Given the absence of a gold standard in humans for this fiber tract, its precise and complete connectivity remains to be determined with certainty. In this study using high angular resolution diffusion MRI (HARDI), we delineated for the first time, six major fiber connections of the human MdLF, four of which are temporo-parietal and two temporo-occipital, by examining morphology, topography, cortical connections, biophysical measures, volume and length in seventy brains. Considering the cortical affiliations of the different connections of MdLF we suggested that this fiber tract may be related to language, attention and integrative higher level visual and auditory processing associated functions. Furthermore, given the extensive connectivity provided to superior temporal gyrus and temporal pole with the parietal and occipital lobes, MdLF may be involved in several neurological and psychiatric conditions such as primary progressive aphasia and other aphasic syndromes, some forms of behavioral variant of frontotemporal dementia, atypical forms of Alzheimer's disease, corticobasal degeneration, schizophrenia as well as attention-deficit/hyperactivity Disorder and neglect disorders. pubtype: Academic Journal doctype: diagnostic images pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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